Evidence map›Paper›PMID 31591551›Full record

ArticleNature biotechnology2020

Genomic and phenotypic analyses of six offspring of a genome-edited hornless bull.

Amy E Young, Tamer A Mansour, Bret R McNabb, Joseph R Owen, Josephine F Trott, C Titus Brown, Alison L Van Eenennaam

Erratum issuedAbstract read
In one paragraph

Article in Nature biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Transgene Mapping in Animals: What to Choose?International journal of molecular sciences · 2025
    Review
  10. Article
  11. Outlook on genome editing application to cattle.Journal of veterinary science · 2024
    Review
  12. Perspectives in Genome-Editing Techniques for Livestock.Animals : an open access journal from MDPI · 2023
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Amy E YoungDepartment of Animal Science, University of California, Davis, CA, USA.ORCID http://orcid.org/0000-0002-4181-4233
Tamer A MansourDepartment of Clinical Pathology, School of Medicine, University of Mansoura, Mansoura, Egypt.ORCID http://orcid.org/0000-0002-4747-4241
Bret R McNabbDepartment of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA, USA.ORCID http://orcid.org/0000-0001-6373-1597
Joseph R OwenDepartment of Animal Science, University of California, Davis, CA, USA.ORCID http://orcid.org/0000-0001-7821-3012
Josephine F TrottDepartment of Animal Science, University of California, Davis, CA, USA.ORCID http://orcid.org/0000-0002-4506-7685
C Titus BrownDepartment of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA, USA.ORCID http://orcid.org/0000-0001-6001-2677
Alison L Van EenennaamDepartment of Animal Science, University of California, Davis, CA, USA. alvaneenennaam@ucdavis.edu.ORCID http://orcid.org/0000-0003-1562-162X

Funding

Pacific Biosciences PacBio RS Single Molecule Real Time SequencerS10OD018174 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI ROKHSAR, DANIEL SOLEYMAN · 2014 to 2014
$600k
Acquisition of Covaris E220 and Sciclone G3 systems for high throughput sequencinS10OD010786 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI COMAI, LUCA · 2012 to 2012
$311k
NIH HHS S10 OD010786NIH HHS S10 OD018174
6 · The paper itself

Abstract

Genome editing followed by reproductive cloning was previously used to produce two hornless dairy bulls. We crossed one genome-edited dairy bull, homozygous for the dominant P

Indexed as

Gene EditingGenomeAllelesAnimalsBase SequenceBreedingCattleChimerismFemaleFetusGenetic LociGenotypeHornsMalePhenotypePhylogeny

Identifiers

PMID31591551
PMCPMC7007412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.