Evidence map›Paper›PMID 31591473›Full record

ArticleCell death and differentiation2020

miR17~92 restrains pro-apoptotic BIM to ensure survival of haematopoietic stem and progenitor cells.

Kerstin Brinkmann, Ashley P Ng, Carolyn A de Graaf, Ladina Di Rago, Craig D Hyland, Eugenio Morelli, Jai Rautela, Nicholas D Huntington, Andreas Strasser, Warren S Alexander and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Cell death and differentiation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. MicroRNA-1224-5p Aggravates Sepsis-Related Acute Lung Injury in Mice.Oxidative medicine and cellular longevity · 2022
    Article
  8. Article
  9. Non-Coding RNAs in Hereditary Kidney Disorders.International journal of molecular sciences · 2021
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Kerstin BrinkmannThe Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.
Ashley P NgThe Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.ORCID http://orcid.org/0000-0001-9690-0879
Carolyn A de GraafThe Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.
Ladina Di RagoThe Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.
Craig D HylandThe Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.
Eugenio MorelliJerome Lipper Multiple Myeloma Centre, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.
Jai RautelaThe Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.ORCID http://orcid.org/0000-0002-4253-9966
Nicholas D HuntingtonThe Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.ORCID http://orcid.org/0000-0002-5267-7211
Andreas StrasserThe Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.
Warren S AlexanderThe Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.
Marco J HeroldThe Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia. herold@wehi.edu.au.ORCID http://orcid.org/0000-0001-7539-7581
The University of Melbourne · AUWalter and Eliza Hall Institute of Medical Research · AUHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The miR17~92 cluster plays important roles in haematopoiesis. However, it is not clear at what stage of differentiation and through which targets miR17~92 exerts this function. Therefore, we generated miR17~92

Indexed as

ApoptosisAnimalsAntigens, CD34Bcl-2-Like Protein 11Cell SurvivalFemaleGene DeletionHematopoietic Stem CellsHumansMaleMice, Inbred C57BLMicroRNAsAntigens, CD34Bcl-2-Like Protein 11MicroRNAsMIRN17-92 microRNA, mouse

Identifiers

PMID31591473
PMCPMC7206080
OpenAlexW2977919159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.