Evidence map›Paper›PMID 31591398›Full record

ArticleNature communications2019

Transient callosal projections of L4 neurons are eliminated for the acquisition of local connectivity.

N S De León Reyes, S Mederos, I Varela, L A Weiss, G Perea, M J Galazo, M Nieto

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 71 citations in OpenAlex.

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  7. Mapping prefrontal afferents along development.Frontiers in neuroscience · 2026
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  8. Prenatal Downregulation of CBThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

N S De León ReyesDepartment of Cellular and Molecular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC), Campus de Cantoblanco, Darwin 3, 28049, Madrid, Spain.ORCID http://orcid.org/0000-0002-4070-5983
S MederosInstituto Cajal, CSIC. Av. Doctor Arce, 37, 28002, Madrid, Spain.ORCID http://orcid.org/0000-0003-0960-9974
I VarelaDepartment of Cellular and Molecular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC), Campus de Cantoblanco, Darwin 3, 28049, Madrid, Spain.
L A WeissDepartment of Cellular and Molecular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC), Campus de Cantoblanco, Darwin 3, 28049, Madrid, Spain.ORCID http://orcid.org/0000-0002-7593-7821
G PereaInstituto Cajal, CSIC. Av. Doctor Arce, 37, 28002, Madrid, Spain.
M J GalazoDepartment of Cell and Molecular Biology and Tulane Brain Institute, Tulane University, 6400 Freret Street, Percival Stern Hall suite 2000, New Orleans, LA, 70118, USA.ORCID http://orcid.org/0000-0003-1909-7765
M NietoDepartment of Cellular and Molecular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC), Campus de Cantoblanco, Darwin 3, 28049, Madrid, Spain. mnlopez@cnb.csic.es.ORCID http://orcid.org/0000-0002-8349-8435
Consejo Superior de Investigaciones Científicas · ESInstituto Cajal · ESTulane University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interhemispheric axons of the corpus callosum (CC) facilitate the higher order functions of the cerebral cortex. According to current views, callosal and non-callosal fates are determined early after a neuron's birth, and certain populations, such as cortical layer (L) 4 excitatory neurons of the primary somatosensory (S1) barrel, project only ipsilaterally. Using a novel axonal-retrotracing strategy and GFP-targeted visualization of Rorb

Indexed as

AnimalsAnimals, NewbornAxonsCorpus CallosumGreen Fluorescent ProteinsMice, Inbred C57BLMice, KnockoutMice, TransgenicMicroscopy, ConfocalNeural PathwaysNeuronsSensory Receptor CellsSomatosensory CortexThalamusGreen Fluorescent Proteins

Identifiers

PMID31591398
PMCPMC6779895
OpenAlexW2977618271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.