Evidence map›Paper›PMID 31591358›Full record

ArticleBiomolecules2019

Can One Define the Conductance of Amino Acids?

Linda A Zotti, Beatrice Bednarz, Juan Hurtado-Gallego, Damien Cabosart, Gabino Rubio-Bollinger, Nicolas Agrait, Herre S J van der Zant

Abstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Electron transport through two interacting channels in Azurin-based solid-state junctions.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Linda A ZottiDepartamento de Física Teoŕica de la Materia Condensada, Universidad Autońoma de Madrid, Ciudad Universitaria de Cantoblanco, E-28049 Madrid, Spain. linda.zotti@uam.es.
Beatrice BednarzKavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands.
Juan Hurtado-GallegoDepartamento de Física Teoŕica de la Materia Condensada, Universidad Autońoma de Madrid, Ciudad Universitaria de Cantoblanco, E-28049 Madrid, Spain.
Damien CabosartKavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands.
Gabino Rubio-BollingerDepartamento de Física Teoŕica de la Materia Condensada, Universidad Autońoma de Madrid, Ciudad Universitaria de Cantoblanco, E-28049 Madrid, Spain.
Nicolas AgraitCondensed Matter Physics Center (IFIMAC), Universidad Autońoma de Madrid, Ciudad Universitaria de Cantoblanco, E-28049 Madrid, Spain.
Herre S J van der ZantKavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands. H.S.J.vanderZant@tudelft.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the electron-transport properties of ten different amino acids and one dimer (di-methionine) using the mechanically controlled break-junction (MCBJ) technique. For methionine and cysteine, additional measurements were performed with the scanning tunneling microscope break-junction (STM-BJ) technique. By means of a statistical clustering technique, we identified several conductance groups for each of the molecules considered. Ab initio calculations revealed that the observed broad conductance distribution stems from the possibility of various binding geometries which can be formed during stretching combined with a multitude of possible conformational changes. The results suggest that it would be helpful to explore different experimental techniques such as recognition tunneling and conditions to help identify the nature of amino-acid-based junctions even further, for example, with the goal to establish a firm platform for their unambiguous recognition by tunneling break-junction experiments.

Indexed as

Amino AcidsCluster AnalysisElectrochemical TechniquesElectron TransportMicroscopy, Scanning TunnelingAmino Acidsamino acidsbiomolecular electronicsbreak junctionsDFTelectron transportNEGF

Identifiers

PMID31591358
PMCPMC6843363

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.