Evidence map›Paper›PMID 31591348›Full record

ReviewNutrients2019

Food Components and Dietary Habits: Keys for a Healthy Gut Microbiota Composition.

Emanuele Rinninella, Marco Cintoni, Pauline Raoul, Loris Riccardo Lopetuso, Franco Scaldaferri, Gabriele Pulcini, Giacinto Abele Donato Miggiano, Antonio Gasbarrini, Maria Cristina Mele

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05457439 (Sustainable-psycho-nutritional Intervention Program and Its Effects on Water and Carbon Footprint, Metabolic Biomarkers, and Gut Microbiota in Mexican Population), which is not on this map. Cited by 345 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
345citing papers in PubMed, 8 pooled it
24.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05457439 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Sustainable-psycho-nutritional Intervention Program and Its Effects on Water and Carbon Footprint, Metabolic Biomarkers, and Gut Microbiota in Mexican Population: a m-Health Randomized Clinical Trial

TypeinterventionalSponsorUniversity of GuadalajaraRan2022 to 2023Enrolled112ConditionsGut Microbiota, Hyperglycemia, Hypercholesterolemia, HDLCArmsSustainable diet promotion through behavioral change intervention
3 · Its place in the literature

Who cites it

345 citing papers in PubMed, 8 syntheses or guidelines pooled it, 644 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Effects of Wilac D001 (Journal of microbiology and biotechnology · 2026
    Trial
  10. Trial
  11. Trial
  12. Trial
  13. Review
  14. Intestinal Epithelial-Protective Effects ofJournal of microbiology and biotechnology · 2026
    Article
  15. Disrupted Gut Viral-Bacterial Ecology of Patients With Liver Cirrhosis.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article

285 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Emanuele RinninellaUOC di Nutrizione Clinica, Dipartimento di Scienze Gastroenterologiche, Endocrino‑Metaboliche e Nefro‑Urologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy. emanuele.rinninella@unicatt.it.
Marco CintoniScuola di Specializzazione in Scienza dell'Alimentazione, Università di Roma Tor Vergata, Via Montpellier 1, 00133 Rome, Italy. marco.cintoni@gmail.com.
Pauline RaoulIstituto di Patologia Speciale Medica, Università Cattolica del Sacro Cuore, Largo F. Vito 1, 00168 Rome, Italy. pauline.raoul1@gmail.com.
Loris Riccardo LopetusoIstituto di Patologia Speciale Medica, Università Cattolica del Sacro Cuore, Largo F. Vito 1, 00168 Rome, Italy. lopetusoloris@libero.it.
Franco ScaldaferriIstituto di Patologia Speciale Medica, Università Cattolica del Sacro Cuore, Largo F. Vito 1, 00168 Rome, Italy. francoscaldaferri@gmail.com.
Gabriele PulciniScuola di Specializzazione in Scienza dell'Alimentazione, Università di Roma Tor Vergata, Via Montpellier 1, 00133 Rome, Italy. gabrielepulcini.med@gmail.com.
Giacinto Abele Donato MiggianoUOC di Nutrizione Clinica, Dipartimento di Scienze Gastroenterologiche, Endocrino‑Metaboliche e Nefro‑Urologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy. giacintoabeledonato.miggiano@policlinicogemelli.it.
Antonio GasbarriniIstituto di Patologia Speciale Medica, Università Cattolica del Sacro Cuore, Largo F. Vito 1, 00168 Rome, Italy. antonio.gasbarrini@unicatt.it.
Maria Cristina MeleUOC di Nutrizione Clinica, Dipartimento di Scienze Gastroenterologiche, Endocrino‑Metaboliche e Nefro‑Urologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy. mariacristina.mele@unicatt.it.
Università Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota is a changing ecosystem, containing trillions of bacteria, continuously shaped by many factors, such as dietary habits, seasonality, lifestyle, stress, antibiotics use, or diseases. A healthy host-microorganisms balance must be respected in order to optimally maintain the intestinal barrier and immune system functions and, consequently, prevent disease development. In the past several decades, the adoption of modern dietary habits has become a growing health concern, as it is strongly associated with obesity and related metabolic diseases, promoting inflammation and both structural and behavioral changes in gut microbiota. In this context, novel dietary strategies are emerging to prevent diseases and maintain health. However, the consequences of these different diets on gut microbiota modulation are still largely unknown, and could potentially lead to alterations of gut microbiota, intestinal barrier, and the immune system. The present review aimed to focus on the impact of single food components (macronutrients and micronutrients), salt, food additives, and different dietary habits (i.e., vegan and vegetarian, gluten-free, ketogenic, high sugar, low FODMAP, Western-type, and Mediterranean diets) on gut microbiota composition in order to define the optimal diet for a healthy modulation of gut microbiota.

Indexed as

DietFeeding BehaviorGastrointestinal MicrobiomeNutritive ValueRecommended Dietary AllowancesBacteriaHost-Pathogen InteractionsHumansIntestinal MucosaPermeabilitydietdietary emulsifiersdietary habitsfood additivesgut microbiota modulationleaky gutlow-calorie sweetenersmacronutrientsmicronutrientsnon-communicable diseasespersonalized medicinesalt

Identifiers

PMID31591348
PMCPMC6835969
OpenAlexW2979096324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.