Evidence map›Paper›PMID 31591287›Full record

ReviewNutrients2019

The Efficacy of Administering Fruit-Derived Polyphenols to Improve Health Biomarkers, Exercise Performance and Related Physiological Responses.

Daniel S Kashi, Akbar Shabir, Mariasole Da Boit, Stephen J Bailey, Matthew F Higgins

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  3. Pooled it
  4. An extract from wholeJournal of the International Society of Sports Nutrition · 2026
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  20. Bioactive Potential of Elderberry (Molecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Daniel S KashiSchool of Human Sciences, Derby University, Kedleston Road, Derby DE22 1GB, UK. D.Kashi@derby.ac.uk.
Akbar ShabirSchool of Human Sciences, Derby University, Kedleston Road, Derby DE22 1GB, UK. A.Shabir2@derby.ac.uk.ORCID 0000-0002-0261-6226
Mariasole Da BoitSchool of Allied Health Sciences, De Montfort University, The Gateway, Leicester LE1 9BH, UK. mariasole.daboit@dmu.ac.uk.
Stephen J BaileySchool of Sport, Exercise and Health Sciences, Loughborough University, Epinal Way, Loughborough LE11 3TU, UK. S.Bailey2@lboro.ac.uk.
Matthew F HigginsSchool of Human Sciences, Derby University, Kedleston Road, Derby DE22 1GB, UK. M.Higgins@derby.ac.uk.ORCID 0000-0002-1051-7850
University of Derby · GBDe Montfort University · GBLoughborough University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyphenols are secondary metabolites involved in a myriad of critical processes in plants. Over recent decades, special attention has been paid to the anti-oxidative role of fruit-derived polyphenols in the human diet, with evidence supporting the contribution of polyphenols in the prevention of numerous non-communicable disease outcomes. However, due to the low concentration in biological fluids in vivo, the antioxidant properties of polyphenols seem to be related to an enhanced endogenous antioxidant capacity induced via signaling through the nuclear respiratory factor 2 pathway. Polyphenols also seem to possess anti-inflammatory and antioxidant properties and have been shown to enhance vascular function via nitric oxide mediated mechanisms. Consequently, there is rationale to support fruit-derived polyphenol supplementation to enhance exercise performance, possibly via improved muscle perfusion. Fruit-derived polyphenol supplementation in exercise studies have included a variety of fruits, e.g., New Zealand blackcurrant, pomegranate, and cherry, in the form of extracts (multicomponent or purified), juices and infusions to varying degrees of benefit. For example, research has yet to link the health-related benefits of black elderberry (

Indexed as

Dietary SupplementsAnimalsAnti-Inflammatory AgentsAntioxidantsExerciseFruitHealth StatusHumansMuscle ContractionMuscle, SkeletalNitric OxideOxidative StressPerformance-Enhancing SubstancesPlant ExtractsPolyphenolsAnti-Inflammatory AgentsAntioxidantsNitric OxidePerformance-Enhancing SubstancesPlant ExtractsPolyphenolsanthocyaninsantioxidanthealthnitric oxidephytochemicalspolyphenols

Identifiers

PMID31591287
PMCPMC6836214
OpenAlexW2978939784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.