ArticleProceedings of the National Academy of Sciences of the United States of America2019
Controlling silk fibroin conformation for dynamic, responsive, multifunctional, micropatterned surfaces.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
25 citing papers in PubMed.
- All-in-one silk-fibroin sustainable high performance electrochemical immunoplatforms: determination of the protein TIM-1 in cancer and allergy scenarios as a case study.Mikrochimica acta · 2026Article
- Visualizing and Quantifying Impact with Mechanochromic Sensing Paints Based on Self-Assembled Polydiacetylene-Silk Core-Shell Vesicles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Development of a Simple and Efficient Method for the Micropatterning of Silk Fibroin.ACS omega · 2026Article
- Engineering conformational transitions in silk fibroin hydrogels to create advanced dynamic microenvironments for biomedical applications.Regenerative biomaterials · 2026Review
- Wrinkling-Based Patterning and Recombinant Spider Silk-Based Coating Technologies - Toward Novel Applications.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Irreproducible SEBS wrinkling based on spin evaporation enabling identifiable artificial finger pad electronics.Nature communications · 2025Article
- Silk Fibroin Surface Engineering Using Phase Separation Approaches for Enhanced Cell Adhesion and Proliferation.ACS applied materials & interfaces · 2025Article
- Chemical and temporal manipulation of early steps in protein assembly tunes the structure and intermolecular interactions of protein-based materials.Protein science : a publication of the Protein Society · 2025Article
- Stimuli-responsive mechanically interlocked polymer wrinkles.Nature communications · 2024Article
- Tuning the Topography of Dynamic 3D Scaffolds through Functional Protein Wrinkled Coatings.Polymers · 2024Article
- MXene-Integrated Silk Fibroin-Based Self-Assembly-Driven 3D-Printed Theragenerative Scaffolds for Remotely Photothermal Anti-Osteosarcoma Ablation and Bone Regeneration.ACS materials Au · 2023Article
- Silk wastes and autoclaved degumming as an alternative for a sustainable silk process.Scientific reports · 2023Article
- Smart Polymer Surfaces with Complex Wrinkled Patterns: Reversible, Non-Planar, Gradient, and Hierarchical Structures.Polymers · 2023Review
- A Silk-Based Platform to Stabilize Phenylalanine Ammonia-lyase for Orally Administered Enzyme Replacement Therapy.Molecular pharmaceutics · 2022Article
- Self-assembled liquid crystal architectures for soft matter photonics.Light, science & applications · 2022Review
- Synergy between silk fibroin and ionic liquids for active gas-sensing materials.Materials today. Bio · 2022Article
- Sustainable Natural Bio-Origin Materials for Future Flexible Devices.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Light-driven dynamic surface wrinkles for adaptive visible camouflage.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Deconstruction and Reassembly of Renewable Polymers and Biocolloids into Next Generation Structured Materials.Chemical reviews · 2021Review
- Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protein micro/nanopatterning has long provided sophisticated strategies for a wide range of applications including biointerfaces, tissue engineering, optics/photonics, and bioelectronics. We present here the use of regenerated silk fibroin to explore wrinkle formation by exploiting the structure-function relation of silk. This yields a biopolymer-based reversible, multiresponsive, dynamic wrinkling system based on the protein's responsiveness to external stimuli that allows on-demand tuning of surface morphologies and properties. The polymorphic transitions of silk fibroin enable modulation of the wrinkle patterns and, consequently, the material's physical properties. The interplay between silk protein chains and external stimuli enables control over the protein film's wrinkling dynamics. Thanks to the versatility of regenerated silk fibroin as a technological substrate, a number of demonstrator devices of varying utility are shown ranging from information encoding to modulation of optical transparency and thermal regulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.