Evidence map›Paper›PMID 31591168›Full record

ArticleInfection and immunity2019

Splenic Innate B1 B Cell Plasmablasts Produce Sustained Granulocyte-Macrophage Colony-Stimulating Factor and Interleukin-3 Cytokines during Murine Malaria Infections.

Shu Shien Chin, Laurent Chorro, John Chan, Grégoire Lauvau

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Malaria: past, present, and future.Signal transduction and targeted therapy · 2025
    Review
  3. Review
  4. Insights into innate immune cell evasion byFrontiers in immunology · 2024
    Review
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  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shu Shien Chin *Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
Laurent Chorro *Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
John ChanDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
Grégoire LauvauDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA gregoire.lauvau@einstein.yu.edu.
Albert Einstein College of Medicine · US

Funding

WORD PROCESSORP30CA013330 · NCI · YESHIVA UNIVERSITY · PI STEVEN C. ALMO · 1985 to 2026
$111.2M
Enhancing Pathogen-specific Memory CD8+ T cell Responses in VivoR01AI103338 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI LAUVAU, GREGOIRE STEPHANE · 2013 to 2022
$5.2M
Geographic Medicine and Emerging InfectionsT32AI070117 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI WEISS, LOUIS M. · 2008 to 2023
$5.1M
IgM in the regulation of TB immunityR01AI139297 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI CHAN, JOHN R. · 2019 to 2023
$3.6M
Early cellular sensing of blood stage Plasmodium Parasites by Innate Immune CellsR21AI122801 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI LAUVAU, GREGOIRE STEPHANE · 2016 to 2017
$459k
Mechanisms of Plasmacytoid dendritic cell activation in vivoR21AI128735 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI FOOKSMAN, DAVID R, LAUVAU, GREGOIRE STEPHANE · 2017 to 2018
$459k
NCI NIH HHS P30 CA013330NIAID NIH HHS R01 AI103338NIAID NIH HHS R01 AI139297NIAID NIH HHS R21 AI122801NIAID NIH HHS R21 AI128735NIAID NIH HHS T32 AI070117
6 · The paper itself

Abstract

The physiopathology of malaria, one of the most deadly human parasitic diseases worldwide, is complex, as it is a systemic disease involving multiple parasitic stages and hosts and leads to the activation of numerous immune cells and release of inflammatory mediators. While some cytokines increased in the blood of patients infected with

Indexed as

AnimalsB-Lymphocyte SubsetsDisease Models, AnimalGranulocyte-Macrophage Colony-Stimulating FactorInterleukin-3Lymphocyte ActivationMalariaMiceMice, Inbred C57BLMice, KnockoutPlasmodium chabaudiPlasmodium yoeliiSignal TransductionSpleenGranulocyte-Macrophage Colony-Stimulating FactorInterleukin-3B1 B cellsGM-CSFIL-3interferon gammaIRA B cellsmalariaplasmablastsPlasmodiumtype I interferon

Identifiers

PMID31591168
PMCPMC6867857
OpenAlexW2978998935

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.