Evidence map›Paper›PMID 31591036›Full record

ArticleCell chemical biology2019

A Catalytic Trisulfide in Human Sulfide Quinone Oxidoreductase Catalyzes Coenzyme A Persulfide Synthesis and Inhibits Butyrate Oxidation.

Aaron P Landry, Sojin Moon, Hanseong Kim, Pramod K Yadav, Arkajit Guha, Uhn-Soo Cho, Ruma Banerjee

Open access · bronzeAbstract read
In one paragraph

Article in Cell chemical biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 63 citations in OpenAlex.

  1. Review
  2. Article
  3. Self-bioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Review
  6. Power and poison: The intersections of HThe Journal of biological chemistry · 2025
    Review
  7. Profiling the landscape of cysteine posttranslational modifications in brain aging and neurodegeneration.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  8. Hydrogen sulfide/polysulfides signaling and neuronal diseases.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. HProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Article
  18. Emerging Chemical Biology of Protein Persulfidation.Antioxidants & redox signaling · 2023
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Aaron P LandryDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Sojin MoonDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Hanseong KimDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Pramod K YadavDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Arkajit GuhaDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Uhn-Soo ChoDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address: uhnsoo@umich.edu.
Ruma BanerjeeDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address: rbanerje@umich.edu.
University of Michigan–Ann Arbor · US

Funding

Sulfide Oxidation and SignalingR35GM130183 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RUMA V BANERJEE · 2019 to 2026
$3.6M
The molecular mechanisms of nutrient- and stress-dependent mTORC1 regulation mediated by human Sestrin2.R01DK111465 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHO, UHN-SOO · 2016 to 2020
$2.4M
Sulfide Oxidation by Human Sulfide Quinone OxidoreductaseF32GM122357 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LANDRY, AARON PAUL · 2017 to 2018
$116k
NIDDK NIH HHS R01 DK111465NIGMS NIH HHS F32 GM122357NIGMS NIH HHS R35 GM130183
6 · The paper itself

Abstract

Mitochondrial sulfide quinone oxidoreductase (SQR) catalyzes the oxidation of H

Indexed as

BiocatalysisButyratesCatalytic DomainCoenzyme ACrystallography, X-RayDisulfidesGlutathioneHumansHydrogen SulfideKineticsMitochondriaOxidation-ReductionProtein BindingProtein Structure, TertiaryQuinone ReductasesSubstrate SpecificityButyratesCoenzyme Acoenzyme A persulfideDisulfidesGlutathioneglutathione persulfideHydrogen SulfideQuinone Reductasessulfide quinone reductaseSulfidesbutyratecoenzyme Qcrystal structureenzyme kineticsflavinhydrogen sulfide

Identifiers

PMID31591036
PMCPMC6906606
OpenAlexW2977567376

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.