Evidence map›Paper›PMID 31590757›Full record

ArticleJournal of food and drug analysis2019

Efficient identification of fungal antimicrobial principles by tandem MS and NMR database.

Ming-Shian Lee, Yu-Liang Yang, Chia-Yen Wu, Ying-Lien Chen, Ching-Kuo Lee, Shean-Shong Tzean, Tzong-Huei Lee

Abstract read
In one paragraph

Article in Journal of food and drug analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ming-Shian LeeSchool of Pharmacy, Taipei Medical University, Taipei, Taiwan.
Yu-Liang YangAgricultural Biotechnology Research Center, Academia Sinica, Taipei, Taiwan.
Chia-Yen WuDepartment of Plant Pathology and Microbiology, National Taiwan University, Taipei, Taiwan.
Ying-Lien ChenDepartment of Plant Pathology and Microbiology, National Taiwan University, Taipei, Taiwan.
Ching-Kuo LeeGraduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan.
Shean-Shong TzeanDepartment of Plant Pathology and Microbiology, National Taiwan University, Taipei, Taiwan.
Tzong-Huei LeeInstitute of Fisheries Science, National Taiwan University, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The continuous re-isolation of the known and non-applicable compounds that is time-consuming and wasting resources is still a critical problem in the discovery of bioactive entities from natural resources.
 To efficiently address the problem, high performance liquid chromatography-diode array detector-microfractionation (HPLC-DAD-microfractionation) guided by disk agar diffusion assay was developed, and the active compounds were further identified using the tandem mass spectrometry (MS/MS)-based molecular networking. Of 150 fungal strains screened, the methanolic extracts of Phoma herbarum PPM7487, Cryptosporiopsis ericae PPM7405, and Albifimbria verrucaria PPM945 exhibited potent antimicrobial activity against Candida albicans SC5314 and Cryptococcus neoformans H99 in the preliminary agar diffusion assay. The concept of OSMAC (one strain many compounds) was employed in the fungal cultures in order to enrich the diversity of the 2

Indexed as

Antifungal AgentsCandida albicansCryptococcus neoformansMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsTandem Mass SpectrometryAntifungal AgentsAlbifimbria verrucariaCryptosporiopsis ericaeDereplicationMolecular networkingPhoma herbarum

Identifiers

PMID31590757
PMCPMC9306986

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.