ArticleTrials2019
Cost analysis and efficacy of recruitment strategies used in a large pragmatic community-based clinical trial targeting low-income seniors: a comparative descriptive analysis.
Article in Trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02579655 (Assessing Outcomes of Enhanced Chronic Disease Care Through Patient Education and a Value-based Formulary Study), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessing Outcomes of Enhanced Chronic Disease Care Through Patient Education and a Value-based Formulary Study
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Recruitment rates and strategies in exercise trials in cancer survivorship: a systematic review.Journal of cancer survivorship : research and practice · 2024Pooled it
- Success and cost-effectiveness of strategies to recruit older adults to a behavioral intervention research study.Contemporary clinical trials · 2025Trial
- Effect on Response Rates of Adding a QR Code to Patient Consent Forms for Qualitative Research in Patients With Cancer: Pilot Randomized Controlled Trial.JMIR formative research · 2025Trial
- Trial
- A comparison of two mail-based strategies to recruit older cancer survivors into a randomized controlled trial of a lifestyle intervention.Journal of cancer survivorship : research and practice · 2022Trial
- Trial
- Exploring patient and pharmacist perspectives on complex interventions for cardiovascular prevention: A qualitative descriptive process evaluation.Health expectations : an international journal of public participation in health care and health policy · 2020Trial
- Measuring Centralized Patient Outreach Recruitment Strategies and their Costs in Clinical Trials.Therapeutic innovation & regulatory science · 2026Article
- Patient Perspectives in Cardiovascular Research: A Qualitative Study of Barriers, Trust, and Strategies for Inclusive Clinical Trials.Circulation. Population health and outcomes · 2026Article
- Zero-Shot Extraction of Seizure Outcomes from Clinical Notes Using Generative Pretrained Transformers.Journal of healthcare informatics research · 2025Article
- A multilevel framework for recruitment and retention in implementation trials: An illustrative example.Clinical trials (London, England) · 2025Article
- Article
- Study protocol for the randomized controlled trial of EMBOLDEN: a multifaceted intervention aimed at Enhancing physical and community MoBility in OLDEr adults with health inequities using commuNity co-design.Frontiers in public health · 2025Article
- Exploring patient perspectives on the impact of resuming cost sharing: a qualitative analysis.Trials · 2024Article
- Recruitment of older adults from long-term care settings for a longitudinal clinical trial.Research in nursing & health · 2024Article
- Evaluation of Eligibility Criteria Relevance for the Purpose of IT-Supported Trial Recruitment: Descriptive Quantitative Analysis.JMIR formative research · 2024Article
- Article
- Embedding research study recruitment within the patient portal preCheck-in.Journal of the American Medical Informatics Association : JAMIA · 2023Article
- Article
- Effectiveness of Facebook Groups and Pages on Participant Recruitment Into a Randomized Controlled Trial During the COVID-19 Pandemic: Descriptive Study.Journal of medical Internet research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
objectiveOne of the most challenging parts of running clinical trials is recruiting enough participants. Our objective was to determine which recruitment strategies were effective in reaching specific subgroups. STUDY DESIGN AND
settingWe assessed the efficacy and costs of the recruitment strategies used in the Assessing Outcomes of Enhanced Chronic Disease Care Through Patient Education and a Value-based Formulary Study (ACCESS) in Alberta, Canada.
resultsTwenty percent of the study budget ($354,330 CAD) was spent on recruiting 4013 participants, giving an average cost per enrolled of $88 CAD. Pharmacies recruited the most participants (n = 1217), at a cost of $128/enrolled. "Paid media" had the highest cost ($806/enrolled), whereas "word of mouth" and "unpaid media" had the lowest (~$3/enrolled). Participants enrolled from "seniors outreach" had the lowest baseline quality of life and income, while participants from "word of mouth" had the lowest educational attainment.
conclusionThe "health care providers" strategies were especially successful - at a moderate cost per enrolled. The "media" strategies were less effective, short lasting, and more costly. No strategy was singularly effective in recruiting our targeted groups, emphasizing the importance of utilizing a variety of strategies to reach recruitment goals.
trial registrationClinicalTrials.gov, NCT02579655 . Registered on 19 October 2015.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.