Evidence map›Paper›PMID 31590474›Full record

ArticleJournal of stroke2019

Duration of Implantable Cardiac Monitoring and Detection of Atrial Fibrillation in Ischemic Stroke Patients: A Systematic Review and Meta-Analysis.

Georgios Tsivgoulis, Aristeidis H Katsanos, Martin Köhrmann, Valeria Caso, Fabienne Perren, Lina Palaiodimou, Spyridon Deftereos, Sotirios Giannopoulos, John Ellul, Christos Krogias and 5 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of stroke, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 7 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 7 syntheses or guidelines pooled it, 83 citations in OpenAlex.

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  6. Insertable cardiac monitors for detection of atrial fibrillation after cryptogenic stroke: a meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
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  20. Multiparametric identification of subclinical atrial fibrillation after an embolic stroke of undetermined source.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 5 countries.

Georgios TsivgoulisSecond Department of Neurology, Attikon Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Aristeidis H KatsanosSecond Department of Neurology, Attikon Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Martin KöhrmannDepartment of Neurology, Essen University Hospital, Essen, Germany.
Valeria CasoStroke Unit, Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy.
Fabienne PerrenDepartment of Neurology, University Hospital of Geneva, Geneva, Switzerland.
Lina PalaiodimouSecond Department of Neurology, Attikon Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Spyridon DeftereosSecond Department of Cardiology, Attikon Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Sotirios GiannopoulosDepartment of Neurology, University of Ioannina School of Medicine, Ioannina, Greece.
John EllulDepartment of Neurology, University Hospital of Patras, School of Medicine, University of Patras, Patras, Greece.
Christos KrogiasDepartment of Neurology, St. Josef-Hospital, Ruhr University, Bochum, Germany.
Dimitris MavridisDepartment of Primary Education, University of Ioannina, Ioannina, Greece.
Sokratis TriantafyllouSecond Department of Neurology, Attikon Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Anne W AlexandrovDepartment of Neurology, University of Tennessee Health Science Center, Memphis, TN, USA.
Peter D SchellingerDepartment of Neurology and Neurogeriatry, Johannes Wesling Medical Center, Ruhr University Bochum, Minden, Germany.
Andrei V AlexandrovDepartment of Neurology, University of Tennessee Health Science Center, Memphis, TN, USA.
University General Hospital Attikon · GRUniversity of Ioannina · GRRuhr University Bochum · DEUniversity of Tennessee Health Science Center · USEssen University Hospital · DENational and Kapodistrian University of Athens · GRUniversity Hospital of Geneva · CHUniversity of Patras · GRUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeCurrent guidelines do not provide firm directions on atrial fibrillation (AF) screening after ischemic stroke (IS). We sought to investigate the association of implantable cardiac monitoring (ICM) duration with the yield of AF detection in IS patients.

methodsWe included studies reporting AF detection rates by ICM in IS patients with negative initial AF screening. We excluded studies reporting prolonged cardiac monitoring with devices other than ICM, not providing AF detection rates or monitoring duration, and reporting overlapping data for the same population. The random-effects model was used for all pooled estimates and meta-regression analyses.

resultsWe included 28 studies (4,531 patients, mean age 65 years). In meta-regression analyses, the proportion of AF detection by ICM was independently associated with monitoring duration (coefficient=0.015; 95% confidence interval [CI], 0.005 to 0.024) and mean patient age (coefficient=0.009; 95% CI, 0.003 to 0.015). No associations were detected with other patient characteristics, including IS subtype (cryptogenic vs. embolic stroke of undetermined source) or time from IS onset to CM implantation. In subgroup analyses, significant differences (P<0.001) in the AF detection rates were found for ICM duration (<6 months: 5% [95% CI, 3% to 6%]; ≥6 and ≤12 months: 21% [95% CI, 16% to 25%]; >12 and ≤24 months: 26% [95% CI, 22% to 31%]; >24 months: 34% [95% CI, 29% to 39%]).

conclusions Extended duration of ICM monitoring and increased patient age are factors that substantially increase AF detection in IS patients with initial negative AF screening.

Indexed as

Atrial fibrillationMeta-analysisMonitoringStroke

Identifiers

PMID31590474
PMCPMC6780018
OpenAlexW2977261591

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.