Evidence map›Paper›PMID 31590437›Full record

Trial reportNutrients2019

Effects of Glycemic Index and Cereal Fiber on Postprandial Endothelial Function, Glycemia, and Insulinemia in Healthy Adults.

Glenn A Gaesser, Jessica Rodriguez, James T Patrie, Corrie M Whisner, Siddhartha S Angadi

Registry-linked trialOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05312788 (Effect of Barley Supplemented Wheat Bread on Markers of Cardiovascular and Renal Health), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05312788 nacompletednot on this mapstarted 2022, after this paper: background citation

Effect of Barley Supplemented Wheat Bread on Markers of Cardiovascular and Renal Health: A Randomized Controlled Trial

TypeinterventionalSponsorKhyber Medical University PeshawarRan2022 to 2022Enrolled25ConditionsCardiovascular Diseases, Kidney DiseasesArmsEffect of Barley Supplemented Wheat Bread on markers of Cardiovascular and Renal Health
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Review
  7. Effects of different types of meals on postprandial glycaemia in healthy subjects.Pediatric endocrinology, diabetes, and metabolism · 2024
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Glenn A GaesserCollege of Health Solutions, Arizona State University, Phoenix, AZ 85004, USA. glenn.gaesser@asu.edu.
Jessica RodriguezSoriant Solutions, Roswell, GA 30075, USA. cwhisner@asu.edu.
James T PatriePublic Health Sciences, University of Virginia, Charlottesville, VA 22903, USA. sangadi@asu.edu.
Corrie M WhisnerCollege of Health Solutions, Arizona State University, Phoenix, AZ 85004, USA. jrvmsv@gmail.com.
Siddhartha S AngadiCollege of Health Solutions, Arizona State University, Phoenix, AZ 85004, USA. jp4h@virginia.edu.
Arizona State University · USEndocrine Research Solutions (United States) · USUniversity of Virginia · US

Funding

Grain Foods Foundation No grant numberNIH HHS RR MO100847
6 · The paper itself

Abstract

Both glycemic index and dietary fiber are associated with cardiovascular disease risk, which may be related in part to postprandial vascular effects. We examined the effects of both glycemic index (GI) and dietary (mainly cereal) fiber on postprandial endothelial function. Eleven adults (5 men; 6 women; age = 42.4 ± 16.1 years; weight = 70.5 ± 10.7 kg; height = 173.7 ± 8.7 cm) consumed four different breakfast meals on separate, randomized occasions: High-Fiber, Low-GI (HF-LGI: Fiber = 20.4 g; GI = 44); Low-Fiber, Low-GI (LF-LGI: Fiber = 4.3 g; GI = 43); Low-Fiber, High-GI (LF-HGI: Fiber = 3.6 g; GI = 70); High-Fiber, High-GI (HF-HGI: Fiber = 20.3 g; GI = 71). Meals were equal in total kcal (~600) and macronutrient composition (~90 g digestible carbohydrate; ~21 g protein; ~15 g fat). The HF-LGI meal resulted in a significant increase in flow-mediated dilation (FMD) 4 hours after meal ingestion (7.8% ± 5.9% to 13.2% ± 5.5%;

Indexed as

BreakfastEdible GrainGlycemic IndexVasodilationAdultBiomarkersBlood GlucoseBrachial ArteryDietary FiberEndothelium, VascularFemaleHealthy VolunteersHumansInsulinMaleMiddle AgedBiomarkersBlood GlucoseDietary FiberInsulincardiovascular diseaseflow-mediated dilationglucoseinsoluble fiberinsulinvascular

Identifiers

PMID31590437
PMCPMC6835298
OpenAlexW2977697836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.