Evidence map›Paper›PMID 31590319›Full record

ArticleMetabolites2019

The Absence of Pyruvate Kinase Affects Glucose-Dependent Carbon Catabolite Repression in

Joana Sousa, Philipp Westhoff, Karen Methling, Michael Lalk

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Microbiology spectrum · 2022
    Article
  5. Wobble Editing ofFrontiers in chemistry · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joana SousaInstitute of Biochemistry, University of Greifswald, 17487 Greifswald, Germany. joanasousa100@gmail.com.
Philipp WesthoffInstitute of Biochemistry, University of Greifswald, 17487 Greifswald, Germany. pd.westhoff@gmail.com.
Karen MethlingInstitute of Biochemistry, University of Greifswald, 17487 Greifswald, Germany. methling@uni-greifswald.de.
Michael LalkInstitute of Biochemistry, University of Greifswald, 17487 Greifswald, Germany. lalk@uni-greifswald.de.
Universität Greifswald · DE

Funding

European Commission 317338
6 · The paper itself

Abstract

Pyruvate is a key intermediate of diverse metabolic pathways of central carbon metabolism. In addition to being the end product of glycolysis, pyruvate is an essential carbon distribution point to oxidative metabolism, amino acid and fatty acid syntheses, and overflow metabolite production. Hence, a tight regulation of pyruvate kinase (Pyk) activity is of great importance. This study aimed to analyze targeted metabolites from several pathways and possible changes in

Indexed as

Bacillus subtiliscarbon catabolite repressionmetabolomicsoverflow metabolitespyruvatepyruvate kinase

Identifiers

PMID31590319
PMCPMC6835821
OpenAlexW2977452726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.