Evidence map›Paper›PMID 31590303›Full record

ArticlePharmaceutics2019

Effect of Size and Concentration of PLGA-PEG Nanoparticles on Activation and Aggregation of Washed Human Platelets.

Rana Bakhaidar, Joshua Green, Khaled Alfahad, Shazia Samanani, Nabeehah Moollan, Sarah O'Neill, Zebunnissa Ramtoola

Abstract read
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rana BakhaidarSchool of Pharmacy and Biological Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland. ranabakhaidar@rcsi.ie.
Joshua GreenSchool of Medicine, Royal College of Surgeons in Ireland, Dublin 2, Ireland. joshuagreen@alumnircsi.com.
Khaled AlfahadSchool of Medicine, Royal College of Surgeons in Ireland, Dublin 2, Ireland. khaledalfahad@rcsi.ie.
Shazia SamananiSchool of Medicine, Royal College of Surgeons in Ireland, Dublin 2, Ireland. shaziasamanani@rcsi.ie.
Nabeehah MoollanSchool of Medicine, Royal College of Surgeons in Ireland, Dublin 2, Ireland. nabeehahmoollan@alumnircsi.com.
Sarah O'NeillSchool of Pharmacy and Biological Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland. zramtoola@rcsi.ie.
Zebunnissa RamtoolaSchool of Pharmacy and Biological Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland. zramtoola@rcsi.ie.

Funding

King Abdulaziz University in Jeddah, Saudi Arabia and the Ministry of Higher Education in Saudi Arabia. N/A
6 · The paper itself

Abstract

Nanotechnology is being increasingly utilised in medicine as diagnostics and for drug delivery and targeting. The small size and high surface area of nanoparticles (NPs), desirable properties that allow them to cross biological barriers, also offer potential for interaction with other cells and blood constituents, presenting possible safety risks. While NPs investigated are predominantly based on the biodegradable, biocompatible, and FDA approved poly-lactide-

Indexed as

activationaggregationbindingnanoparticlesplateletPLGA-PEGuptake

Identifiers

PMID31590303
PMCPMC6835715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.