Evidence map›Paper›PMID 31590269›Full record

ReviewMedicina (Kaunas, Lithuania)2019

Infectious Complications Following Kidney Transplantation-A Focus on Hepatitis C Infection, Cytomegalovirus Infection and Novel Developments in the Gut Microbiota.

Samuel Chan, Nicole M Isbel, Carmel M Hawley, Scott B Campbell, Katrina L Campbell, Mark Morrison, Ross S Francis, E Geoffrey Playford, David W Johnson

Open access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Kynurenine pathway in kidney diseases.Pharmacological reports : PR · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Samuel ChanDepartment of Nephrology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia. samuel.chan@uqconnect.edu.au.
Nicole M IsbelDepartment of Nephrology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia. carmel.hawley@health.qld.gov.au.
Carmel M HawleyDepartment of Nephrology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia. scott.campbell@health.qld.gov.au.
Scott B CampbellDepartment of Nephrology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia. ross.francis@health.qld.gov.au.
Katrina L CampbellAustralasian Kidney Trials Network, The University of Queensland, Brisbane, QLD 4102, Australia. katrina.campbell@health.qld.gov.au.
Mark MorrisonThe University of Queensland Diamantina Institute, Faculty of Medicine, University of Queensland, Woolloongabba, QLD 4102, Australia. m.morrison1@uq.edu.au.
Ross S FrancisDepartment of Nephrology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
E Geoffrey PlayfordAustralasian Kidney Trials Network, The University of Queensland, Brisbane, QLD 4102, Australia.
David W JohnsonDepartment of Nephrology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
Translational Research Institute · AUThe University of Queensland · AUGriffith University · AU

Funding

National Health and Medical Research Council APP1168194Royal Australasian College of Physicians APP1168194
6 · The paper itself

Abstract

The incidence of infectious complications, compared with the general population and the pre-transplant status of the recipient, increases substantially following kidney transplantation, causing significant morbidity and mortality. The potent immunosuppressive therapy given to prevent graft rejection in kidney transplant recipients results in an increased susceptibility to a wide range of opportunistic infections including bacterial, viral and fungal infections. Over the last five years, several advances have occurred that may have changed the burden of infectious complications in kidney transplant recipients. Due to the availability of direct-acting antivirals to manage donor-derived hepatitis C infection, this has opened the way for donors with hepatitis C infection to be considered in the donation process. In addition, there have been the development of medications targeting the growing burden of resistant cytomegalovirus, as well as the discovery of the potentially important role of the gastrointestinal microbiota in the pathogenesis of post-transplant infection. In this narrative review, we will discuss these three advances and their potential implications for clinical practice.

Indexed as

AdultCytomegalovirusCytomegalovirus InfectionsFemaleGastrointestinal MicrobiomeHepacivirusHepatitis CHumansIncidenceKidney TransplantationMaleMiddle AgedPostoperative Complicationscytomegalovirusdirect acting antiviralsdonor-derived infectionsgastrointestinal microbiomehepatitis Ckidney transplantationknowledge acquisitionletermovir

Identifiers

PMID31590269
PMCPMC6843315
OpenAlexW2977539145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.