Evidence map›Paper›PMID 31590208›Full record

ArticleSensors (Basel, Switzerland)2019

Detection of 8-Hydroxy-2'-Deoxyguanosine Biomarker with a Screen-Printed Electrode Modified with Graphene.

Codruta Varodi, Florina Pogacean, Maria Coros, Marcela-Corina Rosu, Raluca-Ioana Stefan-van Staden, Emese Gal, Lucian-Barbu Tudoran, Stela Pruneanu, Simona Mirel

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Codruta VarodiNational Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat Street, Cluj-Napoca 400293, Romania.
Florina PogaceanNational Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat Street, Cluj-Napoca 400293, Romania.
Maria CorosNational Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat Street, Cluj-Napoca 400293, Romania.
Marcela-Corina RosuNational Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat Street, Cluj-Napoca 400293, Romania.
Raluca-Ioana Stefan-van StadenLaboratory of Electrochemistry and PATLAB, National Institute of Research for Electrochemistry and Condensed Matter, 202 Splaiul Independentei Street, Bucharest-6 060021, Romania.
Emese GalDepartment of Chemistry and Chemical Engineering, Hungarian Line of Study, Babes-Bolyai University, 11 Arany János St., Cluj-Napoca 400028, Romania.
Lucian-Barbu TudoranNational Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat Street, Cluj-Napoca 400293, Romania.
Stela PruneanuNational Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat Street, Cluj-Napoca 400293, Romania. stela.pruneanu@itim-cj.ro.
Simona MirelFaculty of Pharmacy, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca 400349, Romania.

Funding

Ministerul Educației și Cercetării Științifice PN-III-P1-1.2-PCCDI-2017-0743 /44PCCDI/2018Ministerul Educației și Cercetării Științifice PN-III-P4-ID-PCCF-2016-0006
6 · The paper itself

Abstract

In this work we present the preparation of graphene material by exfoliation of graphite rods via pulses of current in electrolyte, containing a mixture of boric acid (0.05 M) and sodium chloride (0.05 M). The material was morphologically and structurally characterized by SEM/TEM/HR-TEM, XRD and FTIR techniques. TEM investigation of graphene flakes deposited onto carbon-coated grids allowed the visualization of thin and transparent regions, attributed to few-layer graphene (FLG), as well as thick and dark regions attributed to multi-layer graphene (MLG). The mixed composition of the material was additionally confirmed by XRD, which further indicated that the amount of FLG within the sample was around 83%, while MLG was around 17%. The performance of a screen-printed electrode (SPE) modified with graphene (SPE-Gr) was tested for 8-hydroxy-2'-deoxyguanosine detection. The graphene-modified electrode had a higher sensitivity in comparison with that of SPE, both in standard laboratory solutions (phosphate buffered saline-PBS) and in human saliva.

Indexed as

Biosensing TechniquesElectrochemical Techniques8-Hydroxy-2'-DeoxyguanosineBiomarkersCarbonFilaggrin ProteinsGraphiteHumans8-Hydroxy-2'-DeoxyguanosineBiomarkersCarbonFilaggrin ProteinsFLG protein, humanGraphite8-hydroxy-2′-deoxyguanosineelectrochemical detectiongraphenescreen-printed electrodes

Identifiers

PMID31590208
PMCPMC6806156

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.