Evidence map›Paper›PMID 31589927›Full record

ReviewJournal of biomedical informatics2019

A frame semantic overview of NLP-based information extraction for cancer-related EHR notes.

Surabhi Datta, Elmer V Bernstam, Kirk Roberts

Open access · greenAbstract readReview
In one paragraph

Review in Journal of biomedical informatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 4 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Journal of healthcare informatics research · 2025
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  11. CACER: Clinical concept Annotations for Cancer Events and Relations.Journal of the American Medical Informatics Association : JAMIA · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Surabhi DattaSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, TX, USA.
Elmer V BernstamSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, TX, USA; Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, TX, USA.
Kirk RobertsSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, TX, USA. Electronic address: kirk.roberts@uth.tmc.edu.
Texas Medical Center · USThe University of Texas Health Science Center · USThe University of Texas Health Science Center at Houston · US

Funding

Natural Language Question Understanding for Electronic Health RecordsR00LM012104 · NLM · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ROBERTS, KIRK EDWARD · 2016 to 2018
$747k
NLM NIH HHS R00 LM012104
6 · The paper itself

Abstract

objectiveThere is a lot of information about cancer in Electronic Health Record (EHR) notes that can be useful for biomedical research provided natural language processing (NLP) methods are available to extract and structure this information. In this paper, we present a scoping review of existing clinical NLP literature for cancer.

methodsWe identified studies describing an NLP method to extract specific cancer-related information from EHR sources from PubMed, Google Scholar, ACL Anthology, and existing reviews. Two exclusion criteria were used in this study. We excluded articles where the extraction techniques used were too broad to be represented as frames (e.g., document classification) and also where very low-level extraction methods were used (e.g. simply identifying clinical concepts). 78 articles were included in the final review. We organized this information according to frame semantic principles to help identify common areas of overlap and potential gaps.

resultsFrames were created from the reviewed articles pertaining to cancer information such as cancer diagnosis, tumor description, cancer procedure, breast cancer diagnosis, prostate cancer diagnosis and pain in prostate cancer patients. These frames included both a definition as well as specific frame elements (i.e. extractable attributes). We found that cancer diagnosis was the most common frame among the reviewed papers (36 out of 78), with recent work focusing on extracting information related to treatment and breast cancer diagnosis.

conclusionThe list of common frames described in this paper identifies important cancer-related information extracted by existing NLP techniques and serves as a useful resource for future researchers requiring cancer information extracted from EHR notes. We also argue, due to the heavy duplication of cancer NLP systems, that a general purpose resource of annotated cancer frames and corresponding NLP tools would be valuable.

Indexed as

Electronic Health RecordsNatural Language ProcessingNeoplasmsSemanticsHumansCancerDeep phenotypingElectronic health recordsFrame semanticsNatural language processingScoping review

Identifiers

PMID31589927
PMCPMC11771512
OpenAlexW2934645253

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.