Evidence map›Paper›PMID 31589485›Full record

ArticleCirculation2019

Hemodynamics and Prognostic Impact of Concomitant Mitral Stenosis in Patients Undergoing Surgical or Transcatheter Aortic Valve Replacement for Aortic Stenosis.

Nahoko Kato, Ratnasari Padang, Cristina Pislaru, William R Miranda, Mizuho Hoshina, Kentaro Shibayama, Hiroyuki Watanabe, Christopher G Scott, Kevin L Greason, Sorin V Pislaru and 2 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Circulation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Multiple Valvular Heart Disease in the Transcatheter Era: A State-of-the-Art Review.Structural heart : the journal of the Heart Team · 2024
    Review
  10. Diagnostic Challenges in Aortic Stenosis.Journal of cardiovascular development and disease · 2024
    Review
  11. Article
  12. Review
  13. Article
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  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Nahoko KatoDepartment of Cardiovascular Medicine (N.K., R.P., C.P., W.R.M., S.V.P., V.T.N., P.A.P.), Mayo Clinic, Rochester, MN.
Ratnasari PadangDepartment of Cardiovascular Medicine (N.K., R.P., C.P., W.R.M., S.V.P., V.T.N., P.A.P.), Mayo Clinic, Rochester, MN.
Cristina PislaruDepartment of Cardiovascular Medicine (N.K., R.P., C.P., W.R.M., S.V.P., V.T.N., P.A.P.), Mayo Clinic, Rochester, MN.
William R MirandaDepartment of Cardiovascular Medicine (N.K., R.P., C.P., W.R.M., S.V.P., V.T.N., P.A.P.), Mayo Clinic, Rochester, MN.
Mizuho HoshinaTokyo Bay Urayasu/Ichikawa Medical Center, Urayasu, Japan (M.H., K.S., H.W.).
Kentaro ShibayamaTokyo Bay Urayasu/Ichikawa Medical Center, Urayasu, Japan (M.H., K.S., H.W.).
Hiroyuki WatanabeTokyo Bay Urayasu/Ichikawa Medical Center, Urayasu, Japan (M.H., K.S., H.W.).
Christopher G ScottDepartment of Health Sciences Research (C.G.S.), Mayo Clinic, Rochester, MN.
Kevin L GreasonDepartment of Cardiovascular Surgery (K.L.G.), Mayo Clinic, Rochester, MN.
Sorin V PislaruDepartment of Cardiovascular Medicine (N.K., R.P., C.P., W.R.M., S.V.P., V.T.N., P.A.P.), Mayo Clinic, Rochester, MN.
Vuyisile T NkomoDepartment of Cardiovascular Medicine (N.K., R.P., C.P., W.R.M., S.V.P., V.T.N., P.A.P.), Mayo Clinic, Rochester, MN.
Patricia A PellikkaDepartment of Cardiovascular Medicine (N.K., R.P., C.P., W.R.M., S.V.P., V.T.N., P.A.P.), Mayo Clinic, Rochester, MN.
Mayo Clinic · USMayo Clinic in Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMitral stenosis frequently coexists in patients with severe aortic stenosis. Mitral stenosis severity evaluation is challenging in the setting of combined aortic stenosis and mitral stenosis because of hemodynamic interactions between the 2 valve lesions. The impact of aortic valve replacement (AVR) for severe aortic stenosis on mitral stenosis is unknown. This study aimed to assess the effect of AVR on mitral stenosis hemodynamics and the clinical outcomes of patients with severe aortic stenosis with and without mitral stenosis.

methodsWe retrospectively investigated patients who underwent surgical AVR or transcatheter AVR for severe aortic stenosis from 2008 to 2015. Mean transmitral gradient by Doppler echocardiography ≥4 mm Hg was identified as mitral stenosis; patients were then stratified according to mitral valve area (MVA, by continuity equation) as >2.0 cm

resultsOf 190 patients with severe aortic stenosis and mitral stenosis (age 76±9 years, 42% men), 184 were matched with 362 with severe aortic stenosis without mitral stenosis. Among all mitral stenosis patients, the mean MVA increased after AVR by 0.26±0.59 cm

conclusionsMVA improved after AVR in nearly half of patients with severe aortic stenosis and mitral stenosis. MVA remained ≤2.0 cm

Indexed as

AgedAged, 80 and overEchocardiography, DopplerFemaleFollow-Up StudiesHemodynamicsHumansMaleMitral Valve StenosisPrognosisRetrospective StudiesTranscatheter Aortic Valve Replacementaortic stenosisaortic valve replacementechocardiographymitral stenosis

Identifiers

PMID31589485
OpenAlexW2977927659

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.