Evidence map›Paper›PMID 31589010›Full record

ArticleVeterinary medicine and science2020

Efficacy of enteric-coated tilmicosin granules in pigs artificially infected with Actinobacillus pleuropneumoniae serotype 2.

Zhen Dong, Xu-Zheng Zhou, Ji-Chao Sun, Xiao-Bin Meng, Hong-Sheng Li, Fu-Sheng Cheng, Xiao-Juan Wei, Bing Li, Wei-Wei Wang, Ji-Yu Zhang

Open access · goldAbstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Veterinary medicine and science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
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  3. Veterinary sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Zhen DongLanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences (CAAS), Key Laboratory of Animal Drug production in Ministry of Agriculture, Gansu Province, P. R. China.ORCID 0000-0003-2122-8541
Xu-Zheng ZhouLanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences (CAAS), Key Laboratory of Animal Drug production in Ministry of Agriculture, Gansu Province, P. R. China.
Ji-Chao SunLanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences (CAAS), Key Laboratory of Animal Drug production in Ministry of Agriculture, Gansu Province, P. R. China.
Xiao-Bin MengRingpu Biopharmaceutical Co., Ltd, Tianjin, P. R. China.
Hong-Sheng LiLanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences (CAAS), Veterinary Medicine Engineering Technology Research Centre Gansu Province, Gansu Province, P. R. China.
Fu-Sheng ChengLanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences (CAAS), Key Laboratory of Animal Drug production in Ministry of Agriculture, Gansu Province, P. R. China.
Xiao-Juan WeiLanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences (CAAS), Key Laboratory of Animal Drug production in Ministry of Agriculture, Gansu Province, P. R. China.
Bing LiLanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences (CAAS), Key Laboratory of Animal Drug production in Ministry of Agriculture, Gansu Province, P. R. China.
Wei-Wei WangLanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences (CAAS), Key Laboratory of Animal Drug production in Ministry of Agriculture, Gansu Province, P. R. China.
Ji-Yu ZhangLanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences (CAAS), Key Laboratory of Animal Drug production in Ministry of Agriculture, Gansu Province, P. R. China.
Lanzhou Institute of Husbandry and Pharmaceutical Sciences · CNSino Biopharmaceutical (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPorcine infectious pleuropneumonia caused by Actinobacillus pleuropneumoniae (App) is one of the most serious infectious diseases in pigs and has brought huge economic losses to the world pig industry. The aim of this trial was to evaluate the effect of enteric-coated tilmicosin granule in the treatment and control of artificial infection of App.

methodsSixty Duroc and Yorkshire crossbred pigs (50 of which were artificially infected) were divided into six groups: BCG (Blank control group), ICG (Infection-only control group), HDG (High-dose enteric-coated tilmicosin granules), MDG (Medium-dose enteric-coated tilmicosin granules), LDG (Low-dose enteric-coated tilmicosin granules) and TPG (Tilmicosin premix drug control group). The cure rate, mortality, clinical respiratory score, body temperature score, weight gain, lung score and so on were recorded.

resultsThe cure rate of HDG and MDG was as high as 90%, the mortality was 10%, and the clinical signs recovered quickly.

conclusionThe results showed that enteric-coated tilmicosin granules had obvious therapeutic effect on artificial infection, which could reduce the damage caused by the disease and reduce the mortality.

Indexed as

Actinobacillus InfectionsActinobacillus pleuropneumoniaeAnimalsAnti-Bacterial AgentsFemaleMaleSus scrofaSwineSwine DiseasesTablets, Enteric-CoatedTylosinAnti-Bacterial AgentsTablets, Enteric-CoatedtilmicosinTylosinActinobacillus pleuropneumoniaeartificial infectionenteric-coated granulepigpleuropneumoniaTilmicosin

Identifiers

PMID31589010
PMCPMC7036302
OpenAlexW2979469920

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.