ReviewBiophysical reviews2019
The influence of geometry and other fundamental challenges for bio-sensing with field effect transistors.
Review in Biophysical reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Advanced Materials for Biological Field-Effect Transistors (Bio-FETs) in Precision Healthcare and Biosensing.Advanced healthcare materials · 2025Review
- Integration Strategies and Formats in Field-Effect Transistor Chemo- and Biosensors: A Critical Review.ACS sensors · 2025Review
- Recent advances in bio-integrated electrochemical sensors for neuroengineering.Fundamental research · 2025Review
- Planar Junctionless Field-Effect Transistor for Detecting Biomolecular Interactions.Sensors (Basel, Switzerland) · 2022Article
- Wearable electrochemical biosensors to measure biomarkers with complex blood-to-sweat partition such as proteins and hormones.Mikrochimica acta · 2022Review
- Nanomaterial-Based Biosensors using Field-Effect Transistors: A Review.Journal of electronic materials · 2022Review
- Biosensing based on field-effect transistors (FET): Recent progress and challenges.Trends in analytical chemistry : TRAC · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
We present a review of field effect transistors (FET) from the point of view of their applications to label-free sensing in the era of genomics and proteomics. Here, rather than a collection of Bio-FET achievements, we propose an analysis of the different issues hampering the use of these devices into clinical applications. We make a particular emphasis on the influence of the sensor geometry in the phenomena of mass transport of analytes, which is a topic that has been traditionally overlooked in the analysis and design of biosensors, but that plays a central role in the achievement of low limits of detection. Other issues like the screening of charges by the ions in liquids with physiological ionic strength and the non-specific binding are also reviewed. In conclusion, we give an overview of different solutions that have been proposed to address all these challenges, demonstrating the potential of field effect transistors owing to their ease of integration with other semiconductor components for developing cost-effective, highly multiplexed sensors for next-generation medicines.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.