ArticlePharmacogenomics2019
A stepwise approach to implementing pharmacogenetic testing in the primary care setting.
Article in Pharmacogenomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The trial behind it
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Who cites it
17 citing papers in PubMed.
- Development of an Ancestrally Inclusive Preemptive Pharmacogenetic Testing Panel.Clinical and translational science · 2025Article
- Exploring the Clinical Workflow in Pharmacogenomics Clinics: An Observational Study.Journal of personalized medicine · 2025Article
- Article
- Identifying the prevalence of clinically actionable drug-gene interactions in a health system biorepository to guide pharmacogenetics implementation services.Clinical and translational science · 2023Article
- Pharmacogenomics in practice: a review and implementation guide.Frontiers in pharmacology · 2023Review
- How to Implement a Pharmacogenetics Service at your Institution.Journal of the American College of Clinical Pharmacy : JACCP · 2022Article
- CYP2D6 pharmacogenetics and phenoconversion in personalized medicine.Expert opinion on drug metabolism & toxicology · 2022Review
- Lay understandings of drug-gene interactions: The right medication, the right dose, at the right time, but what are the right words?Clinical and translational science · 2022Article
- Clinical Implementation ofFrontiers in pharmacology · 2022Article
- Underrepresented patient views and perceptions of personalized medication treatment through pharmacogenomics.NPJ genomic medicine · 2021Article
- A Comprehensive Review ofPharmaceuticals (Basel, Switzerland) · 2021Review
- Pharmacogenomic testing to support prescribing in primary care: a structured review of implementation models.Pharmacogenomics · 2021Review
- Creation of a pharmacogenomics patient portal complementary to an existing institutional provider-facing clinical decision support system.JAMIA open · 2021Article
- Assessing the knowledge, perceptions, and practices of primary care clinicians toward pharmacogenetics.Journal of the American College of Clinical Pharmacy : JACCP · 2021Article
- How to Transition from Single-Gene Pharmacogenetic Testing to Preemptive Panel-Based Testing: A Tutorial.Clinical pharmacology and therapeutics · 2020Article
- Genetic testing and results disclosure in diverse populations: what does it take?Genetics in medicine : official journal of the American College of Medical Genetics · 2020Article
- Design and Early Implementation Successes and Challenges of a Pharmacogenetics Consult Clinic.Journal of clinical medicine · 2020Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
Pharmacogenetic testing can help identify primary care patients at increased risk for medication toxicity, poor response or treatment failure and inform drug therapy. While testing availability is increasing, providers are unprepared to routinely use pharmacogenetic testing for clinical decision-making. Practice-based resources are needed to overcome implementation barriers for pharmacogenetic testing in primary care.The NHGRI's IGNITE I Network (Implementing GeNomics In pracTicE; www.ignite-genomics.org) explored practice models, challenges and implementation barriers for clinical pharmacogenomics. Based on these experiences, we present a stepwise approach pharmacogenetic testing in primary care: patient identification; pharmacogenetic test ordering; interpretation and application of test results, and patient education. We present clinical factors to consider, test-ordering processes and resources, and provide guidance to apply test results and counsel patients. Practice-based resources such as this stepwise approach to clinical decision-making are important resources to equip primary care providers to use pharmacogenetic testing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.