Evidence map›Paper›PMID 31588640›Full record

ReviewCell proliferation2020

Long non-coding RNAs in cutaneous biology and proliferative skin diseases: Advances and perspectives.

Lipeng Tang, Yongxin Liang, Hesong Xie, Xiaozhi Yang, Guangjuan Zheng

Open access · goldAbstract readReview
In one paragraph

Review in Cell proliferation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
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  10. Cytotechnology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lipeng TangDepartment of Pharmacology of Traditional Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0002-8760-9331
Yongxin LiangSchool of Bioscience and Bio-pharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Hesong XieSchool of Bioscience and Bio-pharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Xiaozhi YangGuangzhou Virotech Pharmaceutical Co., Ltd, Guangzhou, China.
Guangjuan ZhengDepartment of Pharmacology of Traditional Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0001-5570-2470
Guangdong Pharmaceutical University · CNGuangzhou University of Chinese Medicine · CN

Funding

Medical Scientific Research Foundation of Guangdong Province A2017277National Natural Science Foundation of China 81602748Natural Science Foundation of Guangdong Province 2016A030310291Natural Science Foundation of Guangdong Province 2017A030313639The Specific Research Fund for TCM Science and Technology of Guangdong Provincial Hospital of Chinese Medicine YN2015QN03The Specific Research Fund for TCM Science and Technology of Guangdong Provincial Hospital of Chinese Medicine YN2016YX03The Specific Research Fund for TCM Science and Technology of Guangdong Provincial Hospital of Chinese Medicine YN2018QJ03
6 · The paper itself

Abstract

Advances in transcriptome sequencing have revealed that the genome fraction largely encodes for thousands of non-coding RNAs. Long non-coding RNAs (lncRNAs), which are a class of non-protein-coding RNAs longer than approximately 200 nucleotides in length, are emerging as key epigenetic regulators of gene expression recently. Intensive studies have characterized their crucial roles in cutaneous biology and diseases. In this review, we address the promotive or suppressive effects of lncRNAs on cutaneous physiological processes. Then, we focus on the pathogenic role of dysfunctional lncRNAs in a variety of proliferative skin diseases. These evidences suggest that lncRNAs have indispensable roles in the processes of skin biology. Additionally, lncRNAs might be promising biomarkers and therapeutic targets for cutaneous disorders.

Indexed as

Cell ProliferationAnimalsHumansRNA, Long NoncodingSkinSkin DiseasesRNA, Long Noncodingcutaneous squamous cell carcinomakeratinocyte differentiationlong non-coding RNAsmelanomapsoriasiswound healing

Identifiers

PMID31588640
PMCPMC6985680
OpenAlexW2978208912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.