Evidence map›Paper›PMID 31588331›Full record

ArticleChemical science2019

Nucleophile-intercepted Beckmann fragmentation reactions.

Samuel J Touchette, Evan M Dunkley, Leah L Lowder, Jimmy Wu

Abstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Rapid Access to Conjugated Z,Z,Z-Trienes.Angewandte Chemie (International ed. in English) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Iminologous epoxide ring-closure.Chemical science · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samuel J TouchetteDepartment of Chemistry , Dartmouth College , Hanover , New Hampshire 03755 , USA . Email: jimmy.wu@dartmouth.edu.
Evan M DunkleyDepartment of Chemistry , Dartmouth College , Hanover , New Hampshire 03755 , USA . Email: jimmy.wu@dartmouth.edu.
Leah L LowderDepartment of Chemistry , Dartmouth College , Hanover , New Hampshire 03755 , USA . Email: jimmy.wu@dartmouth.edu.
Jimmy WuDepartment of Chemistry , Dartmouth College , Hanover , New Hampshire 03755 , USA . Email: jimmy.wu@dartmouth.edu.ORCID 0000-0002-0938-8019

Funding

Synthesis and Target Identification of Potent GLP1 SecretagoguesR01GM111638 · NIGMS · DARTMOUTH COLLEGE · PI WU, JIMMY · 2014 to 2018
$1.5M
NIGMS NIH HHS R01 GM111638
6 · The paper itself

Abstract

We describe the first examples of nucleophile-intercepted Beckmann fragmentations of indoline oximes. This reaction uses MsCl as a promoter to give cyano chlorides and is believed to proceed through an aziridinium intermediate

Identifiers

PMID31588331
PMCPMC6761917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.