Evidence map›Paper›PMID 31588329›Full record

ArticleChemical science2019

Using chirality to influence supramolecular gelation.

Kate McAulay, Bart Dietrich, Hao Su, Michael T Scott, Sarah Rogers, Youssra K Al-Hilaly, Honggang Cui, Louise C Serpell, Annela M Seddon, Emily R Draper and 1 more

Abstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Controlling Supramolecular Assembly through Peptide Chirality.ACS applied materials & interfaces · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Reversibly Tuning the Viscosity of Peptide-Based Solutions Using Visible Light.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Process Dependent Complexity in Multicomponent Gels.Macromolecular rapid communications · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kate McAulaySchool of Chemistry , University of Glasgow , Glasgow , G12 8QQ , UK . Email: dave.adams@glasgow.ac.uk.
Bart DietrichSchool of Chemistry , University of Glasgow , Glasgow , G12 8QQ , UK . Email: dave.adams@glasgow.ac.uk.ORCID 0000-0002-4544-4604
Hao SuDepartment of Chemical and Biomolecular Engineering , Whiting School of Engineering , Johns Hopkins University , 3400 North Charles Street , Baltimore , MD 21218 , USA.
Michael T ScottSchool of Chemistry , University of Glasgow , Glasgow , G12 8QQ , UK . Email: dave.adams@glasgow.ac.uk.
Sarah RogersISIS Pulsed Neutron Source , Rutherford Appleton Laboratory , Didcot , OX11 0QX , UK.ORCID 0000-0003-2418-6965
Youssra K Al-HilalySchool of Life Sciences , University of Sussex , Falmer , UK.ORCID 0000-0003-2289-4597
Honggang CuiDepartment of Chemical and Biomolecular Engineering , Whiting School of Engineering , Johns Hopkins University , 3400 North Charles Street , Baltimore , MD 21218 , USA.ORCID 0000-0002-4684-2655
Louise C SerpellSchool of Life Sciences , University of Sussex , Falmer , UK.ORCID 0000-0001-9335-7751
Annela M SeddonSchool of Physics , HH Wills Physics Laboratory , University of Bristol , Tyndall Avenue , Bristol , BS8 1TL , UK.
Emily R DraperSchool of Chemistry , University of Glasgow , Glasgow , G12 8QQ , UK . Email: dave.adams@glasgow.ac.uk.ORCID 0000-0002-3900-7934
Dave J AdamsSchool of Chemistry , University of Glasgow , Glasgow , G12 8QQ , UK . Email: dave.adams@glasgow.ac.uk.ORCID 0000-0002-3176-1350

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most low molecular weight gelators are chiral, with racemic mixtures often unable to form gels. Here, we show an example where all enantiomers, diastereomers and racemates of a single functionalized dipeptide can form gels. At high pH, different self-assembled aggregates are formed and these directly template the structures formed in the gel. Hence, solutions and gels with different properties can be accessed simply by varying the chirality. This opens up new design rules for the field.

Identifiers

PMID31588329
PMCPMC6761870

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.