ArticleChemical science2019
Bio-inspired synthesis of xishacorenes A, B, and C, and a new congener from fuscol.
Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Chemistry and bioactivity of secondary metabolites from South China Sea marine fauna and flora: recent research advances and perspective.Acta pharmacologica Sinica · 2022Review
- Rearrangements of the Chrysanthenol Core: Application to a Formal Synthesis of Xishacorene B.Journal of the American Chemical Society · 2021Article
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Authors and funding
5 authors.
Funding
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Abstract
The xishacorene natural products are structurally unique apolar diterpenoids that feature a bicyclo[3.3.1] framework. These secondary metabolites likely arise from the well-studied, structurally related diterpenoid fuscol. In this manuscript, we describe the conversion of fuscol to xishacorenes A, B, and C, as well as a previously unreported congener, which we have named xishacorene D. In addition, we describe immunomodulatory activity studies of the xishacorenes, a structurally related analogue, and fuscol. These studies were aided by an accurate determination of the physical properties (
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