ArticleChemical science2019
A tetrahedral molecular cage with a responsive vertex.
Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Ring-Opening Alkyne Metathesis Polymerization Catalyzed by a Bench-Stable Rhenium Complex.Journal of the American Chemical Society · 2026Article
- Transfer of structural units through imine exchanges, in solution or without solvent: successive transiminations, stimuli (pH)-modulated covalent switches, and mathematical models.Frontiers in chemistry · 2025Article
- Post-Synthetic Modification of a Porous Hydrocarbon Cage to Give a Discrete CoChemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Purely Covalent Molecular Cages and Containers for Guest Encapsulation.Chemical reviews · 2022Review
- By-design molecular architecturesChemical science · 2021Review
- Highly active alkyne metathesis catalysts operating under open air condition.Nature communications · 2021Article
- Enzymatic Noncovalent Synthesis.Chemical reviews · 2020Review
- Singlet oxygen stimulus for switchable functional organic cages.Chemical science · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dynamic covalent chemistry (DCC) is a widely used method for the self-assembly of three-dimensional molecular architectures. The orthogonality of dynamic reactions is emerging as a versatile strategy for controlling product distributions in DCC, yet the application of this approach to the synthesis of 3D organic molecular cages is limited. We report the first system which employs the orthogonality of alkyne metathesis and dynamic imine exchange to prepare a molecular cage with a reversibly removable vertex. This study demonstrates the rational and controlled application of chemical orthogonality in DCC to prepare organic cages of expanded functionality which respond to chemical stimuli.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.