Evidence map›Paper›PMID 31588228›Full record

ArticleTheranostics2019

Role of FOXC1 in regulating APSCs self-renewal via STI-1/PrP

Yi-Hui Lee, Hsu-Tung Lee, Chien-Lin Chen, Chi-Hao Chang, Chung Y Hsu, Woei-Cherng Shyu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 27 citations in OpenAlex.

  1. FOXC1-ATP7A Axis Activates PI3K/AKT Signaling to Suppress Cuproptosis and Drive Fibroblast Pathogenesis in Rheumatoid Arthritis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yi-Hui LeeTranslational Medicine Research Center, Drug Development Center and Department of Neurology, China Medical University & Hospital, Taichung, Taiwan.
Hsu-Tung LeeDepartment of Neurosurgery, Taichung Veterans General Hospital, Taichung, Taiwan.
Chien-Lin ChenTranslational Medicine Research Center, Drug Development Center and Department of Neurology, China Medical University & Hospital, Taichung, Taiwan.
Chi-Hao ChangTranslational Medicine Research Center, Drug Development Center and Department of Neurology, China Medical University & Hospital, Taichung, Taiwan.
Chung Y HsuGraduate Institute of Biomedical Science and Drug Development Center, China Medical University, Taichung, Taiwan.
Woei-Cherng ShyuTranslational Medicine Research Center, Drug Development Center and Department of Neurology, China Medical University & Hospital, Taichung, Taiwan.
China Medical University Hospital · TWChina Medical University · TWTaichung Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Forkhead box protein C1 (FOXC1) is known to regulate developmental processes in the skull and brain.

Indexed as

AnimalsArachnoidBrain IschemiaCell ProliferationCells, CulturedCell Self RenewalCerebrovascular CirculationFemaleForkhead Transcription FactorsHeat-Shock ProteinsHumansMaleMice, KnockoutNeurogenesisOrgan Culture TechniquesPrPC ProteinsForkhead Transcription FactorsFOXC1 protein, humanFoxc1 protein, mouseHeat-Shock ProteinsPrPC ProteinsSTIP1 protein, humanStip1 protein, mousearachnoid-pia stem cells (APSCs)forkhead box family C1 (FOXC1)stress-inducible protein 1 (STI-1)

Identifiers

PMID31588228
PMCPMC6771253
OpenAlexW2972665711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.