Evidence map›Paper›PMID 31587779›Full record

ReviewCardiology clinics2019

Common Vascular Toxicities of Cancer Therapies.

Joerg Herrmann

Abstract readReview
In one paragraph

Review in Cardiology clinics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Joerg HerrmannDepartment of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, MN 55902, USA. Electronic address: herrmann.joerg@mayo.edu.

Funding

TrAstuzumab Cardiomyopathy Therapeutic Intervention with Carvedilol (TACTIC) TrialR01CA233610 · NCI · MAYO CLINIC ROCHESTER · PI HERRMANN, JOERG, RUDDY, KATHRYN JEAN · 2019 to 2024
$4.3M
The pathophysiological role of the immunoproteasome in atherosclerosisK08HL116952 · NHLBI · MAYO CLINIC ROCHESTER · PI HERRMANN, JOERG · 2014 to 2018
$750k
NCI NIH HHS R01 CA233610NHLBI NIH HHS K08 HL116952
6 · The paper itself

Abstract

The introduction of targeted agents into modern cancer therapy pursued the goal of molecularly more specific, and thereby more effective and safer, therapies. Paradoxically, however, several toxicities were brought to greater attention, among these not only cardiac but also vascular toxicities. The latter reach far beyond venous thromboembolism and include a broad spectrum of presentations based on the vascular territories and pathomechanisms involved, including abnormal vascular reactivity, acute thrombosis, or accelerated atherosclerosis. This article provides an overview of the most common presentations and their management strategies.

Indexed as

Antineoplastic AgentsBlood VesselsCardiotoxicityGlobal HealthHumansIncidenceNeoplasmsRisk FactorsVascular DiseasesAntineoplastic AgentsAtherosclerosisCancerMyocardial infarctionPeripheral arterial diseaseStrokeThrombosisVasospasm

Identifiers

PMID31587779
PMCPMC6995033

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.