Evidence map›Paper›PMID 31587182›Full record

ArticleLa Radiologia medica2020

Characterization of liver nodules in patients with chronic liver disease by MRI: performance of the Liver Imaging Reporting and Data System (LI-RADS v.2018) scale and its comparison with the Likert scale.

Andrea Esposito, Valentina Buscarino, Dario Raciti, Elena Casiraghi, Matteo Manini, Pietro Biondetti, Laura Forzenigo

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in La Radiologia medica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrea EspositoDivision of Radiology, Foundation IRCCS Ca' Granda Maggiore Policlinico Hospital, Via F.Sforza 35, Milan, Italy. andrea.esposito@policlinico.mi.it.ORCID http://orcid.org/0000-0001-6480-0080
Valentina BuscarinoDivision of Radiology, Sant'Andrea Hospital, Corso M. Abbiate 21, Vercelli, Italy.
Dario RacitiDivision of Radiology, Città di Sesto San Giovanni Hospital, Viale G. Matteotti 83, Sesto San Giovanni, Italy.
Elena CasiraghiDepartment of Computer Science (DI), University of Milan, Via G. Celoria 18, Milan, Italy.
Matteo ManiniDepartement of Specialty and Transplant Medicine, Gastroenterology, Hepatology and Transplant Unit, Papa Giovanni XXIII Hospital, Piazza OMS 1, Bergamo, Italy.
Pietro BiondettiDivision of Radiology, Abano Terme Policlinico Hospital, Piazza C. Colombo 1, Abano Terme, Italy.
Laura ForzenigoDivision of Radiology, Foundation IRCCS Ca' Granda Maggiore Policlinico Hospital, Via F.Sforza 35, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the performance of the LI-RADS v.2018 scale by comparing it with the Likert scale, in the characterization of liver lesions.

methodsA total of 39 patients with chronic liver disease underwent MR examination for characterization of 44 liver lesions. Images were independently analyzed by two radiologists using the LI-RADS scale and by another two radiologists using the Likert scale. The reference standard used was either histopathological evaluation or a 4-year MRI follow-up. Receiver operating characteristic analysis was performed.

resultsThe LI-RADS scale obtained an accuracy of 80%, a sensitivity of 72%, a specificity of 93%, a positive predictive value (PPV) of 93% and a negative predictive value (NPV) of 70%, while the Likert scale achieved an accuracy of 79%, a sensitivity of 73%, a specificity of 87%, a PPV of 89% and a NPV of 70%. The area under the curve (AUC) was 85% for the LI-RADS scale and 83% for the Likert scale. The inter-observer agreement was strong (k = 0.89) between the LI-RADS evaluators and moderate (k = 0.69) between the Likert evaluators.

conclusionsThere was no statistically significant difference between the performances of the two scales; nevertheless, we suggest that the LI-RADS scale be used, as it appeared more objective and consistent.

Indexed as

AgedAged, 80 and overCarcinoma, HepatocellularDiagnosis, DifferentialFemaleHumansLiverLiver CirrhosisLiver NeoplasmsMagnetic Resonance ImagingMaleMiddle AgedObserver VariationPrecancerous ConditionsPredictive Value of TestsReference StandardsCarcinoma, hepatocellularData interpretation, statisticalEarly detection of cancerLiver cirrhosisMagnetic resonance imaging

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.