Evidence map›Paper›PMID 31586455›Full record

ArticleMolecular and cellular endocrinology2020

Upregulation of adamts9 by gonadotropin in preovulatory follicles of zebrafish.

Dong Teng Liu, Wan Shu Hong, Shi Xi Chen, Yong Zhu

Open access · greenAbstract read
In one paragraph

Article in Molecular and cellular endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

  1. Dynamic and broad expression of adamts9 in developing and adult zebrafish.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Article
  2. Article
  3. Article
  4. Article
  5. Metalloproteases in gonad formation and ovulation.General and comparative endocrinology · 2021
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Dong Teng LiuState Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Xiamen, Fujian Province, 361102, People's Republic of China.
Wan Shu HongState Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Xiamen, Fujian Province, 361102, People's Republic of China.
Shi Xi ChenState Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Xiamen, Fujian Province, 361102, People's Republic of China. Electronic address: chenshixi@xmu.edu.cn.
Yong ZhuState Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Xiamen, Fujian Province, 361102, People's Republic of China; Department of Biology, East Carolina University, 1000 5th Street, Greenville, NC, 27858, USA. Electronic address: zhuy@ecu.edu.
Xiamen University · CNEast Carolina University · US

Funding

To characterize nongenomic progestin receptors via knockouts in zebrafishR15GM100461 · NIGMS · EAST CAROLINA UNIVERSITY · PI ZHU, YONG · 2013 to 2017
$757k
NIGMS NIH HHS R15 GM100461
6 · The paper itself

Abstract

Previously we had identified adamts9 as a downstream target of Pgr, which is essential for ovulation in zebrafish. The primary goal of this study is to determine whether human chorionic gonadotropin (hCG, LH analog) also regulate adamts9 expression prior to ovulation. The expression of adamts9 was induced by hCG in a dose and time dependent manner in zebrafish preovulatory follicles in vitro. Interestingly, the stimulatory effect of hCG on adamts9 expression was not blocked in pgr

Indexed as

ADAMTS9 ProteinAnimalsChorionic GonadotropinCyclic AMPDose-Response Relationship, DrugFemaleFertilityGene Knockout TechniquesHumansOvarian FollicleReceptors, LHReceptors, ProgesteroneSignal TransductionTime FactorsUp-RegulationZebrafishADAMTS9 Proteinadamts9 protein, zebrafishChorionic GonadotropinCyclic AMPReceptors, LHReceptors, ProgesteroneZebrafish Proteinsadamts9hCGLhcgrOvulationPgrZebrafish

Identifiers

PMID31586455
PMCPMC6878983
OpenAlexW2979033663

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.