ArticleThe Journal of clinical endocrinology and metabolism2020
Associations Between Anti-Mullerian Hormone and Cardiometabolic Health in Reproductive Age Women Are Explained by Body Mass Index.
Article in The Journal of clinical endocrinology and metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Does obesity affect serum anti-müllerian hormone or inhibin B levels in polycystic ovary syndrome? Results of a systematic review and meta-analysis.Reproductive biology and endocrinology : RB&E · 2026Pooled it
- Low anti-Mullerian hormone in reproductive age is associated with MASLD in midlife.Hepatology communications · 2026Article
- Role of cellular prion protein in mouse granulosa cells and its effects on ovarian function in knockout mice.Molecular medicine reports · 2025Article
- High AMH Levels Are Associated With Gestational Hypertension in Patients With PCOS who Underwent IVF/ICSI-ET.The Journal of clinical endocrinology and metabolism · 2025Article
- The Relationship Between Anti-Müllerian Hormone and Body Composition Components in Patients With Polycystic Ovary Syndrome of Reproductive Age.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Association between anti-mullerian hormone and metabolic syndrome: insights from a prospective community-based study.BMC endocrine disorders · 2024Article
- Antimullerian Hormone, a Marker of Ovarian Reserve, Is Protective Against Presence and Severity of NASH in Premenopausal Women.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024Article
- Presence of Fibroids on Transvaginal Ultrasonography in a Community-Based, Diverse Cohort of 996 Reproductive-Age Female Participants.JAMA network open · 2023Article
- Serum Anti-Müllerian Hormone Levels Were Negatively Associated With Body Fat Percentage in PCOS Patients.Frontiers in endocrinology · 2021Article
- Increased Body Mass Index Is Associated With A Nondilutional Reduction in Antimüllerian Hormone.The Journal of clinical endocrinology and metabolism · 2020Article
- The independent associations of anti-Müllerian hormone and estradiol levels over the menopause transition with lipids/lipoproteins: The Study of Women's health Across the Nation.Journal of clinical lipidologyArticle
- Correlation Between Serum AMH Levels and Cardiometabolic Indices in PCOS Women.Indian journal of endocrinology and metabolismArticle
Corrections and comments
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Authors and funding
12 authors at 8 institutions in 1 country.
Funding
Abstract
contextThe relationship between reproductive and cardiometabolic aging is unclear. It is unknown if the relationship differs across different clinical populations.
objectiveTo determine whether markers of ovarian reserve are associated with cardiometabolic risk in reproductive aged women with unexplained infertility (UI), polycystic ovary syndrome (PCOS), and regularly cycling women (OVA). DESIGN AND
settingCross-sectional data from 8 US-based academic centers.
participantsWomen aged 25-40 from 3 clinical populations: 870 with UI, 640 with PCOS, and 921 community-based OVA.
main outcome measuresMultivariable linear regression models were used to relate anti-mullerian hormone (AMH) and antral follicle count with cardiometabolic parameters including body mass index (BMI), waist circumference (WC), fasting glucose and insulin, homeostasis model assessment-insulin resistance (HOMA-IR), lipids, and C-reactive protein.
resultsIn age and study site-adjusted models, AMH inversely related to BMI in the UI and OVA groups (P = 0.02 and P < 0.001). Among women with PCOS, AMH inversely related to BMI (P < 0.001), and also to WC (P < 0.001), fasting insulin (P < 0.01), HOMA-IR (P < 0.01), triglycerides (P = 0.04), and C-reactive protein (P < 0.001) and directly related to higher total (P = 0.02), low-density lipoprotein (P < 0.01), and high-density lipoprotein cholesterol (P < 0.01). In OVA, AMH also varied inversely with WC (P < 0.001), fasting insulin (P = 0.02), and HOMA-IR (P = 0.02). Adjustment for BMI eliminated associations in the OVA group but in PCOS, the relationship of AMH to total (P = 0.03) and low-density lipoprotein cholesterol (P = 0.003) remained.
conclusionAssociations observed between AMH and cardiometabolic indices are largely explained by BMI in women with and without PCOS. (J Clin Endocrinol Metab XX: 0-0, 2019).
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