Evidence map›Paper›PMID 31586173›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2020

Deaths Associated With Hepatitis C Virus Infection Among Residents in 50 States and the District of Columbia, 2016-2017.

Kathleen N Ly, Arialdi M Miniño, Stephen J Liu, Henry Roberts, Elizabeth M Hughes, John W Ward, Ruth B Jiles

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Viral Hepatitis Surveillance in the United States: Then, Now, and Looking Forward.Public health reports (Washington, D.C. : 1974) · 2025
    Article
  8. Article
  9. Article
  10. Health disparities in cirrhosis care and liver transplantation.Nature reviews. Gastroenterology & hepatology · 2025
    Review
  11. Article
  12. Article
  13. Outcomes of Low Barrier Hepatitis C Treatment in High Risk Populations From Primary Care.Journal of community hospital internal medicine perspectives · 2024
    Article
  14. Article
  15. Editorial: Effective Direct-Acting Antiviral Treatments Support Global and National Programs to Eliminate Hepatitis C.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  16. Article
  17. Article
  18. Identification of Genetically Related HCV Infections Among Self-Described Injecting Partnerships.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kathleen N LyDivision of Viral Hepatitis, National Center for Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome, Viral Hepatitis, Sexually Transmitted Disease, and Tuberculosis Prevention, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Arialdi M MiniñoDivision of Vital Statistics, National Center for Health Statistics, US Centers for Disease Control and Prevention, Hyattsville, Maryland, USA, Pittsburg, Pennsylvania, USA.
Stephen J LiuGraduate School of Public Health, University of Pittsburg, Pittsburg, Pennsylvania, USA.
Henry RobertsDivision of Viral Hepatitis, National Center for Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome, Viral Hepatitis, Sexually Transmitted Disease, and Tuberculosis Prevention, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Elizabeth M HughesDivision of Viral Hepatitis, National Center for Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome, Viral Hepatitis, Sexually Transmitted Disease, and Tuberculosis Prevention, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
John W WardCoalition for Global Hepatitis Elimination, The Task Force for Global Health, Decatur, Georgia, USA.
Ruth B JilesDivision of Viral Hepatitis, National Center for Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome, Viral Hepatitis, Sexually Transmitted Disease, and Tuberculosis Prevention, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundMortality associated with hepatitis C virus (HCV) has been well-documented nationally, but an examination across regions and jurisdictions may inform health-care planning.

methodsTo document HCV-associated deaths sub-nationally, we calculated age-adjusted, HCV-associated death rates and compared death rate ratios (DRRs) for 10 US regions, 50 states, and Washington, D.C., using the national rate and described rate changes between 2016 and 2017 to determine variability. We examined the mean age at HCV-associated death, and rates and proportions by sex, race/ethnicity, and birth year.

resultsIn 2017, there were 17 253 HCV-associated deaths, representing 4.13 (95% confidence interval [CI], 4.07-4.20) deaths/100 000 standard population, in a significant, 6.56% rate decline from 4.42 in 2016. Age-adjusted death rates significantly surpassed the US rate for the following jurisdictions: Oklahoma; Washington, D.C.; Oregon; New Mexico; Louisiana; Texas; Colorado; California; Kentucky; Tennessee; Arizona; and Washington (DRRs, 2.87, 2.77, 2.24, 1.62, 1.57, 1.46, 1.36, 1.35, 1.35, 1.35, 1.32, and 1.32, respectively; P < .05). Death rates ranged from a low of 1.60 (95% CI, 1.07-2.29) in Maine to a high of 11.84 (95% CI, 10.82-12.85) in Oklahoma. Death rates were highest among non-Hispanic (non-H) American Indians/Alaska Natives and non-H Blacks, both nationally and regionally. The mean age at death was 61.4 years (range, 56.6 years in West Virginia to 64.1 years in Washington, D.C.), and 78.6% of those who died were born during 1945-1965.

conclusionsIn 2016-2017, the national HCV-associated mortality declined but rates remained high in the Western and Southern regions and Washington, D.C., and among non-H American Indians/Alaska Natives, non-H Blacks, and Baby Boomers. These data can inform local prevention and control programs to reduce the HCV mortality burden.

Indexed as

HepacivirusHepatitis CArizonaColoradoDistrict of ColumbiaHumansKentuckyLouisianaMaineOregonTennesseeTexasUnited StatesWashingtondeathshepatitis Cjurisdictionmortalityregion

Identifiers

PMID31586173
PMCPMC11089524

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.