Evidence map›Paper›PMID 31585955›Full record

ArticleGenetics2019

Nanoluciferase-Based Method for Detecting Gene Expression in

Ivana Sfarcic, Theresa Bui, Erin C Daniels, Emily R Troemel

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Reporter-expressing viruses for antiviral drug discovery research.Frontiers in cellular and infection microbiology · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ivana SfarcicDivision of Biological Sciences, University of California, San Diego, La Jolla, California 92093.ORCID 0000-0001-5681-5688
Theresa BuiDivision of Biological Sciences, University of California, San Diego, La Jolla, California 92093.
Erin C DanielsDivision of Biological Sciences, University of California, San Diego, La Jolla, California 92093.
Emily R TroemelDivision of Biological Sciences, University of California, San Diego, La Jolla, California 92093 etroemel@ucsd.edu.ORCID 0000-0003-2422-0473
University of California, San Diego · US

Funding

The Intracellular Pathogen Response Triggers Defense Against Co-evolved PathogensR01GM114139 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Emily R Troemel · 2015 to 2026
$3.1M
Probing organismal proteostasis through the response to intracellular infectionR01AG052622 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Emily R Troemel · 2017 to 2026
$2.7M
NIA NIH HHS R01 AG052622NIGMS NIH HHS R01 GM114139
6 · The paper itself

Abstract

Genetic reporters such as the green fluorescent protein (GFP) can facilitate measurement of promoter activity and gene expression. However, animal autofluorescence limits the sensitivity of GFP and other fluorescent reporters in whole-animal settings like in the nematode

Indexed as

Gene Expression RegulationAnimalsAnimals, Genetically ModifiedBiological AssayCaenorhabditis elegansGenes, ReporterGreen Fluorescent ProteinsIntestinesLife Cycle StagesLuciferasesNanoparticlesGreen Fluorescent ProteinsLuciferasesC. elegans intestinegenetically encoded reporterintracellular pathogen responseluminescenceNanoluciferase

Identifiers

PMID31585955
PMCPMC6893381
OpenAlexW2978690730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.