ArticlePM & R : the journal of injury, function, and rehabilitation2020
Influence of Antagonistic Hamstring Coactivation on Measurement of Quadriceps Strength in Older Adults.
Article in PM & R : the journal of injury, function, and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 12 citations in OpenAlex.
- Associations of muscle coactivation patterns with gait, muscle strength, and symptoms across different stages of knee osteoarthritis.Knee surgery & related research · 2026Article
- Sensor-Based Monitoring of Knee Osteoarthritis Symptoms in Free-Living Settings: Scoping Review.Journal of medical Internet research · 2026Article
- Manual therapy improves pain and walking function in geriatric knee osteoarthritis via proprioceptive mediation.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Factors, characteristics and influences of the changes of muscle activation patterns for patients with knee osteoarthritis: a review.Journal of orthopaedic surgery and research · 2025Review
- Article
- Biomechanics of the lower limb in patients with mild knee osteoarthritis during the sit-to-stand task.BMC musculoskeletal disorders · 2024Article
- Characteristics of resistance training-based protocols in older adults with sarcopenic obesity: a scoping review of training procedure recommendations.Frontiers in nutrition · 2023Article
- Unilateral Strength Training Imparts a Cross-Education Effect in Unilateral Knee Osteoarthritis Patients.Journal of functional morphology and kinesiology · 2022Article
- Association between hamstring coactivation during isokinetic quadriceps strength testing and knee cartilage worsening over 24 months.Osteoarthritis and cartilage · 2022Article
- Effects of traditional Chinese herb hot compress combined with therapeutic exercise on pain, proprioception, and functional performance among older adults with knee osteoarthritis: A randomized controlled trial.Frontiers in physiology · 2022Article
- Interaction between age and fatigue on antagonist muscle coactivation during an acute post-fatigue recovery phase.Frontiers in aging · 2022Article
- Gastrocnemius Muscle Injury Is the Condition to Induce Cartilage Degeneration of the Rabbit Tibiofemoral Joint: A New Perspective.BioMed research international · 2022Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundThere is limited understanding of how antagonist muscle coactivation relates to measurement of strength in both individuals with and without knee osteoarthritis (KOA).
objectiveThis study sought to determine whether hamstring coactivation during a maximal quadriceps activation task attenuates net quadriceps strength.
designCross-sectional cohort analysis was conducted using data from the 60-month visit of the Multicenter Osteoarthritis Study (MOST).
settingLaboratory.
participantsA sample of 2328 community-dwelling MOST participants between the ages of 55 and 84 years, with or at elevated risk for KOA, completed the 60-month MOST follow-up visit. Of these, 1666 met inclusion criteria for the current study.
interventionsNot applicable. MAIN OUTCOME MEASURE(S): Quadriceps strength; percentage of combined hamstring coactivation (HC), medial HC, and lateral HC. Quadriceps and hamstring strength were assessed using an isokinetic dynamometer. Surface electromyography was used to assess muscle activation patterns. General linear models, adjusted for age, BMI, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Kellgren-Lawrence (KL) grade and study site, modeled the relationship between antagonist hamstring coactivation and quadriceps strength.
resultsMen had significantly greater quadriceps strength (P < .001), history of knee injury (P < .001) and surgery (P = .002), and greater presence of varus malalignment (P < .001). Women had greater pain (P < .001) and proportion of KL grade ≥2 (P = .017). Gender-specific analyses revealed combined HC (P = .013) and lateral HC inversely associated with quadriceps strength in women (P = .023) but not in men (combined HC P = .320, lateral HC P = .755). A nonlinear association was detected between quadriceps strength and medial HC. Assessment of quartiles of medial HC revealed the third quartile had reduced quadriceps strength when compared to the lowest quartile of coactivation in both men and women.
conclusionsHamstring coactivation attenuates measured quadriceps strength in women with or at elevated risk for KOA. LEVEL OF EVIDENCE: II.
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