Evidence map›Paper›PMID 31585357›Full record

SynthesisDrug and alcohol dependence2019

Evidence for state, community and systems-level prevention strategies to address the opioid crisis.

Tamara M Haegerich, Christopher M Jones, Pierre-Olivier Cote, Amber Robinson, Lindsey Ross

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Drug and alcohol dependence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Surveillance for Violent Deaths - National Violent Death Reporting System, 50 States, the District of Columbia, and Puerto Rico, 2023.Morbidity and mortality weekly report. Surveillance summaries (Washington, D.C. : 2002) · 2026
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  17. Trends in prenatal prescription opioid use among Medicaid beneficiaries in Wisconsin, 2010-2019.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tamara M HaegerichNational Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA, 30341, USA. Electronic address: eqd4@cdc.gov.
Christopher M JonesNational Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA, 30341, USA. Electronic address: fjr0@cdc.gov.
Pierre-Olivier CoteNational Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA, 30341, USA. Electronic address: yyc8@cdc.gov.
Amber RobinsonNational Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA, 30341, USA. Electronic address: nkj5@cdc.gov.
Lindsey RossCedars-Sinai Medical Center, USA. Electronic address: Lindsey.Ross@cshs.org.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundPractitioners and policy makers need evidence to facilitate the selection of effective prevention interventions that can address the ongoing opioid overdose epidemic in the United States.

methodsWe conducted a systematic review of publications reporting on rigorous evaluations of systems-level interventions to address provider and patient/public behavior and prevent prescription and illicit opioid overdose. A total of 251 studies were reviewed. Interventions studied included 1) state legislation and regulation, 2) prescription drug monitoring programs (PDMPs), 3) insurance strategies, 4) clinical guideline implementation, 5) provider education, 6) health system interventions, 7) naloxone education and distribution, 8) safe storage and disposal, 9) public education, 10) community coalitions, and 11) interventions employing public safety and public health collaborations.

resultsThe quality of evidence supporting selected interventions was low to moderate. Interventions with the strongest evidence include PDMP and pain clinic legislation, insurance strategies, motivational interviewing in clinical settings, feedback to providers on opioid prescribing behavior, intensive school and family-based programs, and patient education in the clinical setting.

conclusionsAlthough evidence is growing, further high-quality research is needed. Investigators should aim to identify strategies that can prevent overdose, as well as influence public, patient, and provider behavior. Identifying which strategies are most effective at addressing prescription compared to illicit opioid misuse and overdose could be fruitful, as well as investigating synergistic effects and unintended consequences.

Indexed as

Community ParticipationDrug OverdoseDrug StorageEducation, ContinuingEvaluation Studies as TopicGuideline AdherenceHealth EducationHumansOpioid EpidemicPrescription Drug Monitoring ProgramsPublic HealthUnited StatesOpioidOverdosePolicyPrescribingPrevention

Identifiers

PMID31585357
PMCPMC9286294

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.