Evidence map›Paper›PMID 31585209›Full record

ArticleNeuroscience letters2019

Characterization of stimulus response curves obtained with transcranial magnetic stimulation from bilateral tibialis anterior muscles post stroke.

Pooja C Iyer, Sangeetha Madhavan

Open access · greenAbstract read
In one paragraph

Article in Neuroscience letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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  4. Combining transcranial direct current stimulation with aerobic exercise to optimize cortical priming in stroke.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pooja C IyerGraduate Program in Rehabilitation Science, College of Applied Health Sciences, University of Illinois, Chicago, IL, USA.
Sangeetha MadhavanBrain Plasticity Laboratory, Department of Physical Therapy, College of Applied Health Sciences, University of Illinois, Chicago, IL, USA. Electronic address: smadhava@uic.edu.
University of Illinois Urbana-Champaign · US

Funding

Cortical priming to optimize gait rehabilitation post strokeR01HD075777 · NICHD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MADHAVAN, SANGEETHA · 2014 to 2024
$4.1M
NICHD NIH HHS R01 HD075777
6 · The paper itself

Abstract

backgroundStimulus response curves (SR curves), measured using transcranial magnetic stimulation (TMS) induced motor evoked potentials (MEP), yield important information regarding corticomotor connectivity. Limited understanding of SR curve analyses techniques for leg muscles after stroke may limit the utility of TMS data for walking recovery.

objectiveTo compare linear and non-linear curve fitting for MEP responses from the non-paretic and paretic tibialis anterior (TA) muscles.

methodsAccuracy of fit was measured using coefficient of determination (R

resultsThe non-linear function demonstrated higher R

conclusionOur results highlight the differences between non-linear and linear approaches to best fit the SR curves from bilateral TA muscles in stroke survivors. Although the linear function can appropriately fit the SR curve of the paretic and non-paretic TA, the non-linear function estimated a higher slope. We found the AUC to be a more robust measure that was not affected by the type of curve-fitting approach and only the AUC of the paretic TA showed significant association with walking speeds. A better understanding of SR curve fitting approaches for the TA muscles in individuals with chronic stroke allows for their optimal use in interpretation of TMS data and literature.

Indexed as

Nonlinear DynamicsArea Under CurveElectromyographyEvoked Potentials, MotorFemaleHumansMaleMiddle AgedMuscle, SkeletalParesisRandomized Controlled Trials as TopicRetrospective StudiesStrokeTranscranial Magnetic StimulationWalking SpeedArea under recruitment curveBoltzmann fitLinear regressionLower limbStimulus response curvesStroke

Identifiers

PMID31585209
PMCPMC7226675
OpenAlexW2977351771

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.