Evidence map›Paper›PMID 31585050›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Adiponectin deficiency induces mitochondrial dysfunction and promotes endothelial activation and pulmonary vascular injury.

Dilip Shah, Claudio Torres, Vineet Bhandari

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Adipose Tissue Inflammation and Pulmonary Dysfunction in Obesity.International journal of molecular sciences · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Activation of PPARPPAR research · 2022
    Article
  15. Article
  16. Review
  17. Targeting alveolar-specific succinate dehydrogenase A attenuates pulmonary inflammation during acute lung injury.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dilip ShahDepartment of Pediatrics, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Claudio TorresDepartment of Neurobiology and Anatomy, Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Vineet BhandariDepartment of Pediatrics, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Drexel University · US

Funding

Cellular Senescence and Alzheimer’s diseaseR56AG056696 · NIA · DREXEL UNIVERSITY · PI TORRES, CLAUDIO AURELIO · 2018 to 2018
$391k
NIA NIH HHS R56 AG056696
6 · The paper itself

Abstract

Adiponectin (APN), an adipocyte-derived adipokine, has been shown to limit lung injury originating from endothelial cell (EC) damage. Previously we reported that obese mice with low circulatory APN levels exhibited pulmonary vascular endothelial dysfunction. This study was designed to investigate the cellular and molecular mechanisms underlying the pulmonary endothelium-dependent protective effects of APN. Our results demonstrated that in APN

Indexed as

InflammasomesAdiponectinAnimalsEndothelium, VascularLipopolysaccharidesLung InjuryMaleMetabolism, Inborn ErrorsMiceMice, Inbred C57BLMice, KnockoutMice, ObeseMitochondriaNLR Family, Pyrin Domain-Containing 3 ProteinOrganelle BiogenesisVascular System InjuriesAdiponectinAdipoq protein, mouseInflammasomesLipopolysaccharidesNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseacute lung injuryadipokineendothelial dysfunctionPGC-1α mitochondria biogenesis

Identifiers

PMID31585050
PMCPMC6894062
OpenAlexW2978327561

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.