Evidence map›Paper›PMID 31584879›Full record

ArticleAging2019

Hypermethylated long noncoding RNA MEG3 promotes the progression of gastric cancer.

Lei Ding, Yuan Tian, Ling Wang, Miaomiao Bi, Dengke Teng, Sen Hong

Abstract read
In one paragraph

Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Role of miR‑181a‑5p in cancer (Review).International journal of oncology · 2023
    Review
  10. Article
  11. Gastric cancer: An epigenetic view.World journal of gastrointestinal oncology · 2022
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lei DingDepartment of Radiology, China-Japan Union Hospital of Jilin University, Changchun 130022, Jilin, China.
Yuan TianDepartment of Medical Examination, China-Japan Union Hospital of Jilin University, Changchun 130022, Jilin,China.
Ling WangDepartment of Gynecology and Obstetrics, The Second Hospital of Jilin University, Changchun 130041, Jilin, China.
Miaomiao BiDepartment of Ophthalmology, China-Japan Union Hospital of Jilin University, Changchun, 130022, Jilin, China.
Dengke TengDepartment of Ultrasonography, China-Japan Union Hospital of Jilin University, Changchun 130022, Jilin, China.
Sen HongDepartment of Colorectal and Anal Surgery, The First Hospital of Jilin University, Changchun 130000, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to explore the expression and degree of methylation of lncRNA MEG3 in gastric cancer tissues and to analyze its effect on the migration and proliferation of gastric cancer patients and the mechanism by which this occurs. The targeting relationship between MEG3, miR-181a-5p and

Indexed as

AnimalsCell LineFemaleGene Expression Regulation, NeoplasticH(+)-K(+)-Exchanging ATPaseHumansMiceMice, NudeMicroRNAsNeoplasms, ExperimentalRNA, Long NoncodingStomach NeoplasmsATP4A protein, humanAtp4a protein, mouseH(+)-K(+)-Exchanging ATPaseMEG3 non-coding RNA, humanMicroRNAsMIrn181 microRNA, humanmirn181 microRNA, mouseRNA, Long NoncodingATP4Bgastric cancerMEG3methylationmiR-181a-5p

Identifiers

PMID31584879
PMCPMC6814614

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.