Trial reportBiomedica : revista del Instituto Nacional de Salud2019
Effects of high-intensity interval training compared to moderate-intensity continuous training on maximal oxygen consumption and blood pressure in healthy men: A randomized controlled trial
Trial report in Biomedica : revista del Instituto Nacional de Salud, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of a High-intensity Interval Training Program Compared to a Moderate Intensity Program in Adults 18-44 Years
Comparison of High-Intensity Interval Training and Medium-Intensity Interval Training on Cardiopulmonary Fitness, Strength and Agility in Athletes
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Optimising Exercise Prescription: A Meta-Analysis Examining the Dose Response of Exercise Duration on Cardiorespiratory Fitness Following HIIT and MICT.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- High-intensity interval training versus moderate-intensity continuous training for localized prostate cancer under active surveillance: a systematic review and network meta-analysis.Prostate cancer and prostatic diseases · 2025Pooled it
- Effect of therapeutic exercise on peak oxygen consumption in oncological population: a systematic review with meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Comparing The Effects of Small-Sided Handball Games and High-Intensity Interval Training on The Physical Health and Fitness of Untrained Individuals: A 16-Week Randomized Controlled Study.Journal of sports science & medicine · 2026Trial
- Effects of combined high-intensity interval and moderate-intensity continuous training vs. moderate-intensity continuous training alone in male adolescents: a randomized controlled trial.Scientific reports · 2025Trial
- Hippocampal subfield plasticity is associated with improved spatial memory.Communications biology · 2024Trial
- Effects of High Intensity Interval Training versus Sprint Interval Training on Cardiac Autonomic Modulation in Healthy Women.International journal of environmental research and public health · 2022Trial
- High-intensity interval training for reducing blood pressure: a randomized trial vs. moderate-intensity continuous training in males with overweight or obesity.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Trial
- Comparing four training modalities on body composition, cardiorespiratory fitness and cardiovascular responses in sedentary young men: a randomized trial.BMC sports science, medicine & rehabilitation · 2026Article
- Aerobic Exercise Training and VOJournal of functional morphology and kinesiology · 2026Review
- HIIT versus MICT on Blood Pressure and Cardiac Biomarkers in L-NAME-induced Hypertensive Rats.International journal of exercise science · 2026Article
- Narrative Review of High-Intensity Interval Training: Positive Impacts on Cardiovascular Health and Disease Prevention.Journal of cardiovascular development and disease · 2025Review
- Exercise workload: a key determinant of immune health - a narrative review.Frontiers in immunology · 2025Review
- Article
- Effects of Aerobic Exercise Versus High-Intensity Interval Training on V̇O2max and Blood Pressure.Cureus · 2022Review
- Effects of low-volume, high-intensity interval training on maximal oxygen consumption, body fat percentage and health-related quality of life in women with overweight: A randomized controlled trial.Journal of exercise science and fitness · 2022Article
- Upper and lower limb resistance training program versus high-intensity interval training on oxidative stress markers in university athletes.Journal of exercise rehabilitation · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAerobic exercise generates increased cardiorespiratory fitness, which results in a protective factor for cardiovascular disease. High-intensity interval training (HIIT) might produce higher increases on cardiorespiratory fitness in comparison with moderate-intensity continuous training (MICT); however, current evidence is not conclusive.
objectiveTo compare the effects of a low-volume HIIT and a MICT on maximal oxygen consumption (VO2max), systolic blood pressure, and diastolic blood pressure during eight weeks in healthy men between 18 and 44 years of age. MATERIALS AND
methodsWe conducted a randomized controlled trial. Forty-four volunteers were randomized to HIIT (n=22) or MICT (n=22). Both groups performed 24 sessions on a treadmill. The HIIT group completed 15 bouts of 30 seconds (90-95%, maximal heart rate, HRmax), while the MICT group completed 40 minutes of continuous exercise (65-75% HRmax). Results: Intra-group analysis showed an increase in VO2max of 3.5 ml/kg/min [95% confidence interval (CI) 2.02 to 4.93; p=0.0001] in HIIT and 1.9 ml/kg/min (95% CI -0.98 to 4.82; p=0.18) in MICT. However, the difference between the two groups was not statistically significant (1.01 ml/kg/min. 95% CI -2.16 to 4.18, p=0.52). MICT generated a greater reduction in systolic blood pressure compared to HIIT (median 8 mm Hg; p<0.001). No statistically significant differences were found between the groups for DBP.
conclusionsResults indicated no significant change in VO2max with a low-volume HIIT protocol versus MICT after 24 sessions. In contrast, MICT provided a greater reduction in systolic blood pressure compared to HIIT. The study is registered as a clinical trial via clinicaltrials.gov with identifier number: NCT02288403.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.