Evidence map›Paper›PMID 31584561›Full record

ArticleRetina (Philadelphia, Pa.)2020

VASOPROLIFERATIVE TUMORS IN INTERMEDIATE UVEITIS.

Francesco Pichi, Piergorgio Neri, Aniruddha Agarwal, Alessandro Invernizzi, Netan Choudhry, Radgonde Amer, Andrea Lembo, Paolo Nucci, Ian Thompson, H Nida Sen and 1 more

Open access · greenAbstract readCase ReportsMulticenter Study
In one paragraph

Article in Retina (Philadelphia, Pa.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

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  7. Stand-alone pars plana vitrectomy versus pars plana vitrectomy with retinopexy for retinal vasoproliferative tumors.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 5 countries.

Francesco PichiCleveland Clinic Abu Dhabi, Eye Institute, Abu Dhabi, United Arab Emirates.
Piergorgio NeriCleveland Clinic Abu Dhabi, Eye Institute, Abu Dhabi, United Arab Emirates.
Aniruddha AgarwalAdvanced Eye Center, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Alessandro InvernizziEye Clinic, Department of Biomedical and Clinical Science 'Luigi Sacco', Luigi Sacco Hospital, University of Milan, Milan, Italy.
Netan ChoudhryVitreous Retina Macula Specialists of Toronto, Toronto, Canada.
Radgonde AmerHadassah Medical Center, Jerusalem, Israel.
Andrea LemboSan Giuseppe Hospital, University Eye Clinic, Milan, Italy.
Paolo NucciSan Giuseppe Hospital, University Eye Clinic, Milan, Italy.
Ian ThompsonNational Eye Institute, National Institute of Health, Bethesda, Maryland; and.
H Nida SenNational Eye Institute, National Institute of Health, Bethesda, Maryland; and.
Carol L ShieldsOcular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.
National Eye Institute · USOspedale San Giuseppe · ITCase Western Reserve University · USCleveland Clinic Lerner College of Medicine · USHadassah Medical Center · ILPost Graduate Institute of Medical Education and Research · INUniversity of Sydney · AUWills Eye Hospital · US

Funding

Intramural NIH HHS Z99 EY999999
6 · The paper itself

Abstract

purposeTo describe patients with intermediate uveitis complicated by vasoproliferative tumors (VPTs).

methodsData were collected at seven Uveitis/Ocular Oncology centers on demographic, ophthalmic findings at baseline and at follow-up, and on imaging. The therapeutic intervention, final visual acuity, and duration of follow-up were recorded.

resultsA total of 36 eyes from 34 patients (12 men, 22 women; mean age 35.3 ± 14.2 years) were included in this study. Visual acuity at presentation ranged from 20/40 to counting fingers. At the time of VPT diagnosis, intermediate uveitis was active in all eyes. The mean VPT thickness was 3.06 ± 0.86 mm. Local treatment to the VPT was provide in 22 eyes (61.1%) and no local treatment to the VPT in 14 eyes (38.9%). After the VPT was detected, systemic or local treatment for the inflammation was initiated and on follow-up FAs 94.4% of the eyes showed resolution of the vascular leakage. During follow-up of 35.8 months, the 22 VPTs treated locally had a reduction in the tumor thickness to 1.25 mm, whereas the 14 VPTs untreated remained stable (final mean tumor thickness 2.65 mm).

conclusionThe presence of active intermediate uveitis accompanied by VPTs suggests the need for an aggressive uveitis treatment.

Indexed as

AdolescentAdultChildFemaleFluorescein AngiographyHumansLaser TherapyMaleMiddle AgedNeoplasms, Vascular TissueRetinal NeoplasmsRetinal VesselsRetrospective StudiesTomography, Optical CoherenceUltrasonographyUveitis, Intermediate

Identifiers

PMID31584561
PMCPMC7108969
OpenAlexW2978254430

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.