Evidence map›Paper›PMID 31584447›Full record

ArticleAnatolian journal of cardiology2019

Frontal QRS-T angle is related with hemodynamic significance of coronary artery stenosis in patients with single vessel disease.

Serkan Kahraman, Ali Kemal Kalkan, Ayse Beril Turkyilmaz, Arda Can Dogan, Yalcin Avci, Fatih Uzun, Mehmet Erturk

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Article in Anatolian journal of cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Serkan KahramanDepartment of Cardiology, University of Health Sciences, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital; İstanbul-Turkey.
Ali Kemal KalkanDepartment of Cardiology, University of Health Sciences, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital; İstanbul-Turkey.
Ayse Beril TurkyilmazDepartment of Cardiology, University of Health Sciences, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital; İstanbul-Turkey.
Arda Can DoganDepartment of Cardiology, University of Health Sciences, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital; İstanbul-Turkey.
Yalcin AvciDepartment of Cardiology, University of Health Sciences, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital; İstanbul-Turkey.
Fatih UzunDepartment of Cardiology, University of Health Sciences, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital; İstanbul-Turkey.
Mehmet ErturkDepartment of Cardiology, University of Health Sciences, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital; İstanbul-Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFractional flow reserve (FFR) measurement is used to decide the hemodynamic significance of coronary artery lesion. QRS-T angle (QRSTa) is a novel marker of myocardial repolarization abnormality and is affected by obstructive coronary artery disease. The aim of the present study was to evaluate the association between QRSTa and coronary FFR measurement in patients with isolated left anterior descending (LAD) artery stenosis.

methodsA total of 197 patients undergoing FFR measurement for isolated LAD artery stenosis were retrospectively enrolled in the present study. According to FFR value, patients were divided into two groups as 139 patients with normal FFR (>0.80, group 1) and 58 patients with low FFR (≤0.80, group 2). A 12-lead surface electrocardiography of all subjects that had been recorded before performing coronary angiography was evaluated to measure QRSTa, as well as baseline demographic and clinical variables.

resultsThe mean age of group 2 was significantly higher than that of group 1 (61±11 and 64±11, p=0.044). While there were no differences in heart rate, QRS duration, and corrected QT interval between the two groups, QT interval [377 (359-397) and 379 (367-410), p=0.045] and frontal QRSTa [59 (10-120) and 86 (22-132), p<0.001] were higher in group 2. QT interval [odds ratio (OR)=1.046, 95% confidence interval (CI)=1.010-1.084, p=0.012] and frontal QRSTa (OR=1.025, 95% CI=1.010-1.041, p=0.001) were found to be independent predictors of low FFR value in multivariate logistic regression analysis.

conclusionIn the present study, FFR measurement was demonstrated to be correlated with wide QRSTa as a noninvasive and easy method. Thus, we suggest that the results of FFR measurement as an invasive modality can be previously predicted with a simple electrocardiographic evaluation, such as QRSTa.

Indexed as

HemodynamicsAgedAngina, StableCoronary StenosisElectrocardiographyExercise TestFemaleFractional Flow Reserve, MyocardialHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisRetrospective StudiesROC CurveSensitivity and Specificity

Identifiers

PMID31584447
PMCPMC6955084

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.