ReviewCurrent pediatric reviews2020
Eosinophilic Esophagitis in Children: Clinical Findings and Diagnostic Approach.
Review in Current pediatric reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed.
- Dupilumab Efficacy in Children With Eosinophilic Esophagitis With Prior Swallowed Topical Corticosteroid Use: A Subgroup Analysis.The American journal of gastroenterology · 2026Trial
- Pediatric eosinophilic esophagitis: diagnostic and therapeutic insights from a 15-year retrospective study.European journal of pediatrics · 2026Article
- Incidental finding of esophageal eosinophilia in patients investigated for suspected celiac disease: results from a pediatric retrospective study.European journal of pediatrics · 2026Article
- Clinical Patterns and Outcomes of Eosinophilic Esophagitis in Children and Adolescents at a Tertiary Care Center in Lebanon.Children (Basel, Switzerland) · 2026Article
- Eosinophilic esophagitis in children: Clinical perspectives and evolving therapeutic strategies.World journal of gastrointestinal endoscopy · 2026Review
- Recommendations for the diagnosis and management of eosinophilic esophagitis in adults and children in Canada: a Delphi consensus project.Journal of the Canadian Association of Gastroenterology · 2025Review
- Recommendations for the diagnosis and management of eosinophilic esophagitis in adults and children in Canada: a Delphi consensus project.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025Review
- Cow milk protein allergy mimics in infancy.World journal of clinical pediatrics · 2025Review
- There is a long way from current clinical practice in Denmark compared to recent published English guideline on management of children with eosinophilic oesophagitis.BMC pediatrics · 2024Article
- Eosinophilic oesophagitis in a Nigerian adolescent: a case report.The Pan African medical journal · 2024Article
- Eosinophilic Esophagitis-What Do We Know So Far?Journal of clinical medicine · 2023Review
- Clinical Features of Eosinophilic Esophagitis: A Single Center Experience in Ecuador.Pediatric gastroenterology, hepatology & nutrition · 2022Article
- The incidence of eosinophilic oesophagitis in 2007-2017 among children in North Denmark Region is lower than expected.BMC pediatrics · 2022Article
- Esophageal Dysphagia in Children: State of the Art and Proposal for a Symptom-Based Diagnostic Approach.Frontiers in pediatrics · 2022Review
- Sleep in children with eosinophilic esophagitis.World journal of pediatrics : WJP · 2021Article
- Increase in foreign body and harmful substance ingestion and associated complications in children: a retrospective study of 1199 cases from 2005 to 2017.BMC pediatrics · 2020Article
- Nationwide Multicenter Study of Eosinophilic Esophagitis in Korean Children.Pediatric gastroenterology, hepatology & nutrition · 2020Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Eosinophilic esophagitis (EoE) is an emerging chronic immune and antigen-mediated clinicopathologic disease. During the last 2 decades, the incidence of this condition in children has increased significantly, thanks to practitioners for creating the awareness and higher use of diagnostic endoscopy. We have analysed paediatric literature on EoE focusing on the epidemiology, pathophysiology, clinical findings and diagnostic approach. EoE is pathogenically related to a Th2 inflammation characterized by a mixed IgE and non-IgEmediated reaction to food and/or environmental agents. This leads to esophageal dysfunction and remodeling accompanied by subepithelial fibrosis. EoE can be presented with several range of gastrointestinal symptoms, including regurgitation, vomiting, feeding difficulties or feeding refusal in infants and toddlers, as well as heartburn, dysphagia and food bolus impaction in older children and adults. The diagnostic suspicion is based on the presence of chronic symptoms of esophgeal dysfunction and esophageal eosinophilia characterised histologically by a significant eosinophilic infiltration of the oesophageal mucosa (>15 eosinophils per high powered field). In this review, we will provide an update on clinical presentation and diagnostic approach to EoE in children. We emphasized on the relevant aspects of the new clinical condition termed "PPI responsive esophageal eosinophilia", as entities distinct from EoE and the role of PPI trial in the diagnostic workup, therefore we proposed a new diagnostic algorithm.
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