ArticleChembiochem : a European journal of chemical biology2020
A Fast and Easy Method for Specific Detection of Circular RNA by Rolling-Circle Amplification.
Article in Chembiochem : a European journal of chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Diagnostic and prognostic role of circular RNAs: Analytical challenges and emerging opportunities.iScience · 2026Review
- Detection of mutant cancer-derived circRNAs in extracellular vesicles by rolling circle amplification.Molecular therapy. Nucleic acids · 2026Article
- Review
- Accurate Reconstruction of Circular RNAs from Complex Rolling Circular Long Reads with CircPlex.bioRxiv : the preprint server for biology · 2025Article
- A Comprehensive multi-network analysis of ceRNAs and transcription factors for papillary thyroid carcinoma diagnosis and prognosis.Scientific reports · 2025Article
- CircPrime: a web-based platform for design of specific circular RNA primers.BMC bioinformatics · 2023Article
- Review
- Roles of circRNAs in hematological malignancies.Biomarker research · 2022Review
- BmCPV-Derived Circular DNA vcDNA-S7 Mediated byFrontiers in immunology · 2022Article
- Article
- Article
- CircRNAs and their regulatory roles in cancers.Molecular medicine (Cambridge, Mass.) · 2021Review
- Article
- JEDI: circular RNA prediction based on junction encoders and deep interaction among splice sites.Bioinformatics (Oxford, England) · 2021Article
- Rolling Circle Amplification as a Universal Method for the Analysis of a Wide Range of Biological Targets.Russian journal of bioorganic chemistry · 2021Article
- The Role and Clinical Potentials of Circular RNAs in Prostate Cancer.Frontiers in oncology · 2021Review
- A Fast and Easy Method for Specific Detection of Circular RNA by Rolling-Circle Amplification.Chembiochem : a European journal of chemical biology · 2020Article
Corrections and comments
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Authors and funding
2 authors.
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Abstract
Circular RNAs (circRNAs) represent a new class of usually noncoding transcripts with largely unknown functions. Their research is hampered not least by the inapplicability of traditional analytical methods. Herein we describe a rapid and easy assay for the detection of natural circRNA, based on rolling-circle amplification (RCA). This technique does not require the use of fluorescently labeled RNA or DNA and can specifically detect circular RNA in the presence of a 1000-fold excess of the same linear RNA. Only standard devices such as (quantitative) PCR cyclers and gel electrophoresis are used.
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Registered trials
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