Evidence map›Paper›PMID 31584127›Full record

ReviewCellular and molecular life sciences : CMLS2019

Distinct functions of TMC channels: a comparative overview.

Xiaomin Yue, Yi Sheng, Lijun Kang, Rui Xiao

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 54 citations in OpenAlex.

  1. CaProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Hair cell apoptosis and deafness inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Genomic and transcriptomic analyses illuminate the molecular basis of the unique lifestyle of a tubeworm, Lamellibrachia satsuma.DNA research : an international journal for rapid publication of reports on genes and genomes · 2023
    Article
  12. Review
  13. The conductance and organization of the TMC1-containing mechanotransducer channel complex in auditory hair cells.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  14. Article
  15. Review
  16. New Tmc1 Deafness Mutations Impact Mechanotransduction in Auditory Hair Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  17. Article
  18. Review
  19. Functional Role of Class III Myosins in Hair Cells.Frontiers in cell and developmental biology · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Xiaomin YueDepartment of Neurosurgery of the First Affiliated Hospital, Institute of Neuroscience, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou, China.
Yi ShengDepartment of Aging and Geriatric Research, Institute on Aging, University of Florida, Gainesville, FL, USA.
Lijun KangDepartment of Neurosurgery of the First Affiliated Hospital, Institute of Neuroscience, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou, China. kanglijun@zju.edu.cn.ORCID http://orcid.org/0000-0001-9939-5134
Rui XiaoDepartment of Aging and Geriatric Research, Institute on Aging, University of Florida, Gainesville, FL, USA. rxiao@ufl.edu.ORCID http://orcid.org/0000-0001-5541-6685
University of Florida · USFirst Affiliated Hospital Zhejiang University · CNZhejiang University · CN

Funding

American Cancer Society RSG-17-171-01-DMCAmerican Federation for Aging Research 17146Fundamental Research Funds for the Central Universities 2018FZA7004National Natural Science Foundation of China 31471023National Natural Science Foundation of China 31771113Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences 2018PT31041
6 · The paper itself

Abstract

In the past two decades, transmembrane channel-like (TMC) proteins have attracted a significant amount of research interest, because mutations of Tmc1 lead to hereditary deafness. As evolutionarily conserved membrane proteins, TMC proteins are widely involved in diverse sensorimotor functions of many species, such as hearing, chemosensation, egg laying, and food texture detection. Interestingly, recent structural and physiological studies suggest that TMC channels may share a similar membrane topology with the Ca

Indexed as

AnimalsHearing LossHumansIon ChannelsMechanotransduction, CellularMutation, MissenseNeuronsProprioceptionProtein IsoformsIon ChannelsProtein IsoformsC. elegansDrosophilaHearingMechanosensationMembrane excitabilityTMC channelsZebrafish

Identifiers

PMID31584127
PMCPMC11105308
OpenAlexW2977710046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.