Evidence map›Paper›PMID 31583618›Full record

Observational studyQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020

Factors contributing to the ceiling effect of the EQ-5D-5L: an analysis of patients with prostate cancer judged "no-problems".

Hideki Murasawa, Takayuki Sugiyama, Yuki Matsuoka, Takashi Okabe, Yoshiaki Wakumoto, Nobumichi Tanaka, Mikio Sugimoto, Masafumi Oyama, Kiyohide Fujimoto, Shigeo Horie and 4 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hideki MurasawaDepartment of Life Sciences, Ritsumeikan University, Kusatsu, Japan. h-mura@fc.ritsumei.ac.jp.ORCID http://orcid.org/0000-0003-4897-1239
Takayuki SugiyamaDepartment of Urology, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Yuki MatsuokaDepartment of Urology, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Takashi OkabeDepartment of Uro-Oncology, Saitama Medical University International Medical Center, Saitama, Japan.
Yoshiaki WakumotoDepartment of Urology Juntendo University, Graduate School of Medicine, Tokyo, Japan.
Nobumichi TanakaDepartment of Urology, Nara Medical University, Kashihara, Japan.
Mikio SugimotoDepartment of Urology, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Masafumi OyamaDepartment of Uro-Oncology, Saitama Medical University International Medical Center, Saitama, Japan.
Kiyohide FujimotoDepartment of Urology, Nara Medical University, Kashihara, Japan.
Shigeo HorieDepartment of Urology Juntendo University, Graduate School of Medicine, Tokyo, Japan.
Masaru FunagoshiDepartment of Life Sciences, Ritsumeikan University, Kusatsu, Japan.
Ichiro ArakawaFaculty of Pharmaceutical Science, Teikyo Heisei University, Tokyo, Japan.
Shinichi NotoDepartment of Rehabilitation, Niigata University of Health and Welfare, Niigata, Japan.
Kojiro ShimozumaDepartment of Life Sciences, Ritsumeikan University, Kusatsu, Japan.

Funding

Japan Society for the Promotion of Science JP16K08894Japan Society for the Promotion of Science JP26293116
6 · The paper itself

Abstract

purposeThe goal of the present study was to determine factors related to a ceiling effect (CE) on the EQ-5D-5L among Japanese patients with prostate cancer (PC).

methodsAn existent cross-sectional observational study dataset was used. Patients were ≥ 20 years of age and diagnosed with PC. For CE determinants on the EQ-5D-5L, we excluded possible "full-health" patients flagged by the EQ-VAS (score = 100) and/or FACT-P (score = 156) instruments. We then divided them into binary variables: A CE group (EQ-5D-5L score = 1) and others (< 1). The associations between CE, sociodemographic and medical characteristics, and FACT-P subscale scores were examined using a multivariate LASSO selection followed by a binomial logistic regression analysis performed to calculate odds ratios (ORs) and 95% confidence intervals (CIs).

resultsA total of 362 patients were analyzed. The LASSO selection variables, including all obtained variables, were as follows: age, palliative treatment, FACT-P physical well-being, and PC subscale score. Statistically significant variables predicting CE were palliative treatment (OR 0.23; 95% CI 0.09-0.60), physical well-being (OR 1.54; 95% CI 1.34-1.76), and PC subscale (OR 1.08; 95% CI 1.03-1.14).

conclusionsThis study revealed that palliative treatment and two FACT-P physical well-being and PC subscale scores were positively related to CE on the EQ-5D-5L. To our knowledge, this is the first study to examine predictors of CE on the EQ-5D-5L. The present results may be helpful for facilitating the consideration of "bolt-on" studies from the standpoint of PC patients.

Indexed as

Health StatusAdultAgedCross-Sectional StudiesHumansJapanMaleMiddle AgedPalliative CareProstatic NeoplasmsPsychometricsQuality of LifeSurveys and QuestionnairesYoung AdultCeiling effectEQ-5D-5LFACT-PHealth-related quality of life (HRQoL)Prostate cancer

Identifiers

PMID31583618
PMCPMC7028791

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.