Evidence map›Paper›PMID 31583488›Full record

Observational studyMagma (New York, N.Y.)2020

Severe pulmonary regurgitation in adolescents with tetralogy of Fallot leads to increased longitudinal strain.

Pekka Ylitalo, Lauri Lehmonen, Kirsi Lauerma, Miia Holmström, Olli Pitkänen-Argillander, Eero Jokinen

Open access · hybridAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Magma (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Right-left ventricular shape variations in tetralogy of Fallot: associations with pulmonary regurgitation.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Pekka YlitaloChildren's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Lauri LehmonenHUS Medical Imaging Center, Radiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. lauri.lehmonen@helsinki.fi.ORCID http://orcid.org/0000-0002-7523-3867
Kirsi LauermaHUS Medical Imaging Center, Radiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Miia HolmströmHUS Medical Imaging Center, Radiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Olli Pitkänen-ArgillanderChildren's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Eero JokinenChildren's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
University of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPostoperative patients with tetralogy of Fallot (TOF) are often compromised by chronic pulmonary regurgitation and chronic right ventricular volume load. We sought to determine whether pulmonary regurgitation (PR) would affect right and left ventricle (RV and LV) strain. MATERIALS AND

methodsThis cross-sectional analysis included 40 patients who had TOF with surgical repair, with an average follow-up period of 11.8 ± 3.0 years. Altogether, 44 healthy volunteers with similar age and gender distribution were recruited. A cardiovascular magnetic resonance imaging study with feature tracking analysis was performed on all patients and controls.

resultsRV peak longitudinal strain was increased in TOF patients with PR > 30 ml/m

conclusionsPediatric patients with TOF and a severe pulmonary regurgitation show an enhanced longitudinal strain when compared to patients with milder regurgitation or to control subjects. In addition, mean RV circumferential strain of the patients is significantly enhanced compared to healthy individuals.

Indexed as

AdolescentAngiographyCase-Control StudiesCross-Sectional StudiesFemaleHeartHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleProspective StudiesPulmonary Valve InsufficiencyStroke VolumeTetralogy of FallotVentricular Dysfunction, LeftAdolescentCardiovascular magnetic resonanceFeature trackingStrainTetralogy of Fallot

Identifiers

PMID31583488
PMCPMC7109171
OpenAlexW2978194292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.