ArticleWorld journal of surgery2020
Burden of Neonatal Surgical Conditions in Northern Ghana.
Article in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 47 citations in OpenAlex.
- Mortality and Factors Associated with Death in Children with Congenital Gastrointestinal Malformations-A Five-Year Retrospective Study from Romania (2020-2024).Children (Basel, Switzerland) · 2026Article
- Whole exome sequencing uncovers genetic syndromes and putative candidate genes underlying orofacial clefts presenting with limb abnormalities in a Sub-Saharan African cohort.BMC medical genomics · 2026Article
- Developing and validating a neonatal screening tool for congenital anomalies to be used in low- and middle-income country settings.BMJ global health · 2026Article
- Whole Exome Sequencing Uncovers Genetic Syndromes Associated with Orofacial Clefts presenting with Limb abnormalities in a Sub-Saharan African cohort.Research square · 2025Article
- A retrospective outpatient department-based study of the pattern of first-visit pediatric neurosurgical disorders: a 6-year single-center experience in Ghana.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Time to Death and Predictors Among Neonates with Neural Tube Defects in Two Public Hospitals, Addis Ababa, Ethiopia: A Retrospective Follow-Up Study.Pediatric health, medicine and therapeutics · 2025Article
- GAPS Phase III: incorporation of capacity based weighting in the global assessment for pediatric surgery.Pediatric surgery international · 2024Article
- Infant mortality in Ghana: investing in health care infrastructure and systems.Health affairs scholar · 2024Article
- Increasing access to pediatric surgical care: Assessing district hospital readiness in rural Rwanda.World journal of surgery · 2024Article
- Impact of the COVID-19 pandemic on perinatal care and outcomes: A retrospective study in a tertiary hospital in Northern Ghana.PloS one · 2024Article
- Modeling the global impact of reducing out-of-pocket costs for children's surgical care.PLOS global public health · 2024Article
- A scoping review of the post-discharge care needs of babies requiring surgery in the first year of life.PLOS global public health · 2023Article
- The state of surgery, obstetrics, trauma, and anaesthesia care in Ghana: a narrative review.Global health action · 2022Review
- Factors associated with mortality in congenital malformations of the gastrointestinal tract in a tertiary center in Senegal.World journal of pediatric surgery · 2022Article
- Paediatric surgical outcomes in sub-Saharan Africa: a multicentre, international, prospective cohort study.BMJ global health · 2021Article
- A retrospective review of gastroschisis epidemiology and referral patterns in northern Ghana.Pediatric surgery international · 2021Article
- Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study.Lancet (London, England) · 2021Article
- Global and regional overview of the inclusion of paediatric surgery in the national health plans of 124 countries: an ecological study.BMJ open · 2021Article
- A qualitative study of Ghanaian pediatric oncology nurses' care practice challenges.BMC nursing · 2021Article
- Decrease in Admissions and Change in the Diagnostic Landscape in a Newborn Care Unit in Northern Ghana During the COVID-19 Pandemic.Frontiers in pediatrics · 2021Article
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Authors and funding
10 authors at 6 institutions in 3 countries.
Funding
Abstract
backgroundCongenital anomalies have risen to become the fifth leading cause of under-five mortality globally. The majority of deaths and disability occur in low- and middle-income countries including Ghana. This 3-year retrospective review aimed to define, for the first time, the characteristics and outcomes of neonatal surgical conditions in northern Ghana.
methodsA retrospective study was conducted to include all admissions to the Tamale Teaching Hospital (TTH) neonatal intensive care unit (NICU) with surgical conditions between January 2014 and January 2017. Data were collected on demographics, diagnosis and outcomes. Descriptive analysis was performed on all data, and logistic regression was used to predict determinants of neonatal mortality. p < 0.05 was deemed significant.
resultsThree hundred and forty-seven neonates were included. Two hundred and sixty-one (75.2%) were aged 7 days or less at presentation, with males (n = 177, 52%) slightly higher than females (n = 165, 48%). The majority were delivered by spontaneous vaginal delivery (n = 247, 88%); 191 (58%) were born in hospital. Congenital anomalies accounted for 302 (87%) of the neonatal surgical cases and 45 (96%) deaths. The most common anomalies were omphalocele (n = 48, 13.8%), imperforate anus (n = 34, 9.8%), intestinal obstruction (n = 29, 8.4%), spina bifida (n = 26, 7.5%) and hydrocephalus (n = 19, 5.5%). The overall mortality rate was 13.5%. Two-thirds of the deaths (n = 30) from congenital anomalies were conditions involving the digestive system with gastroschisis having the highest mortality of 88%. Omphalocele (n = 11, 23.4%), gastroschisis (n = 7, 14.9%) and imperforate anus (n = 6, 12.8%) contributed to the most deaths. On multivariate analysis, low birthweight was significantly associated with mortality (OR 3.59, CI 1.4-9.5, p = 0.009).
conclusionCongenital anomalies are a major global health problem associated with high neonatal mortality in Ghana. The highest burden in terms of both caseload and mortality is attributed to congenital anomalies involving the digestive system, which should be targeted to improve outcomes.
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