ArticleInternational journal of reproductive biomedicine2019
Knowledge and attitude toward genetic diseases and genetic tests among pre-marriage individuals: A cross-sectional study in northern Iran.
Article in International journal of reproductive biomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Machine learning improves detection of alpha thalassemia carriers compared to clinical features.Scientific reports · 2025Article
- Article
- Consanguineous marriages, premarital screening, and genetic testing: a survey among Saudi university students.Frontiers in public health · 2024Article
- Toward Integration of Pharmacogenomic Tests into Daily Clinical Practice: A General Survey for Polish Healthcare Workers.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- Exploring People's Knowledge of Genetics and Attitude towards Genetic Testing: A Cross-Sectional Study in a Population with a High Prevalence of Consanguinity.Healthcare (Basel, Switzerland) · 2022Article
- Knowledge and attitudes regarding genetic testing among Jordanians: An approach towards genomic medicine.Saudi journal of biological sciences · 2021Article
- Attitude and awareness of public towards genetic testing in Riyadh, Saudi Arabia.Saudi journal of biological sciences · 2021Article
- Parental genetic knowledge and attitudes toward childhood genetic testing for inherited eye diseases.Molecular genetics & genomic medicine · 2020Article
- Knowledge, Awareness, and Perception of Genetic Testing for Hereditary Disorders Among Malaysians in Klang Valley.Frontiers in genetics · 2020Article
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGenetic testing has been widely introduced for many hereditary disorders. While the attitudes towards these facilities have been evaluated in many countries, there are only a few reports on the knowledge of and the orientation among Iranians.
objectiveThe current study assesses the attitudes and knowledge of pre-marriage individuals toward the availability and use of genetic tests. MATERIALS AND
methodsA comprehensive questionnaire was distributed among 408 marrying individuals. The questions addressed the demographic characteristics along the registration of participant's knowledge, education, and attitude toward genetic testing. The individuals were divided into three groups based on their knowledge: 1) Scored above 80 to 100 were defined as "good" 2) 60 to 80 as "average" 3) less than 60 as "poor" knowledge.
resultsMost participants (86%) believed consanguineous marriages increase the risk of genetic diseases; 82.3% knew that thalassemia is a type of genetic disease, only 33.3% could distinguish prenatal diagnosis (PND) from other laboratory tests. The relationship between the participants' knowledge and their level of education was significant (r░=░0.78, p░<░0.001), age (r= -0.16, p░<░0.01), and urbanity (p░<░0.01). A prominent relationship was observed between the knowledge (r░=░0.64, p░<░0.001) or education (r░=░0.62, p░<░0.001) and people's desire to use the genetic tests before the wedding ceremony. No significant correlations were found between the participant's attitude and their ages/urbanity. Most of the individuals agreed to arrange a genetic counseling before marriage (0.94%).
conclusionThis study revealed that most individuals were interested in using genetic counseling services and genetic tests before marriage.
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