Evidence map›Paper›PMID 31583352›Full record

ArticlePain reports

Effect of sustained experimental muscle pain on joint position sense.

Simon J Summers, Siobhan M Schabrun, Rogerio P Hirata, Thomas Graven-Nielsen, Rocco Cavaleri, Lucy S Chipchase

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pain reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Simon J SummersSchool of Science and Health, Western Sydney University, Penrith, New South Wales, Australia.
Siobhan M SchabrunNeuroscience Research Australia, Sydney, New South Wales, Australia.
Rogerio P HirataDepartment of Health Science and Technology, SMI, Aalborg University, Aalborg, Denmark.
Thomas Graven-NielsenDepartment of Health Science and Technology, Center for Neuroplasticity and Pain (CNAP), SMI, Faculty of Medicine, Aalborg University, Aalborg, Denmark.
Rocco CavaleriSchool of Science and Health, Western Sydney University, Penrith, New South Wales, Australia.
Lucy S ChipchaseSchool of Science and Health, Western Sydney University, Penrith, New South Wales, Australia.
Western Sydney University · AUAalborg University · DKNeuroscience Research Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionJoint position sense (JPS) is impaired in clinical musculoskeletal pain conditions, but when this impairment develops in the transition from initial to prolonged pain is not known.

objectivesThis study assessed whether progressively developing sustained experimentally induced muscle pain impacts JPS in healthy individuals.

methodsTwenty-eight healthy individuals received injection of nerve growth factor (NGF) into the right extensor carpi radialis brevis muscle on days 0 and 2 to induce sustained pain and hyperalgesia. Wrist JPS was assessed 2 days before day 0 (day -2), before the injection on days 0 and 2, and on days 4 and 14. Joint position sense was quantified as the ability to return the wrist to a neutral position following movements in the direction of radial and ulnar deviation. A 3-dimensional motion analysis system was used to calculate absolute, relative, and joint-angle repositioning errors. Numerical rating scale scores of pain intensity, body chart pain drawings, and pressure pain thresholds (PPTs) were recorded on each day.

resultsCompared with baseline, pressure pain thresholds decreased while pain intensity and area increased at day 2 (

conclusionDespite the presence of sustained muscle pain and hyperalgesia for 4 days at the elbow, no statistical change in wrist joint position error was observed. These findings suggest that pain and hyperalgesia lasting as long as 4 days does not impair JPS.

Indexed as

Experimental painJoint position senseMusculoskeletal painNerve growth factorProprioception

Identifiers

PMID31583352
PMCPMC6749891
OpenAlexW2926841683

What OpenQuestion holds

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LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.